agouti-related peptide

agouti-related peptide (AgRP),

a peptide released with neuropeptide Y from specific neurons of the arcuate nucleus. These neurons are stimulated by ghrelin and inhibited by neuropeptide PYY and leptin. Release of agouti-related peptide and neuropeptide Y stimulates appetite while reducing metabolism.
See also: ghrelin, leptin, neuropeptide Y.

Farlex Partner Medical Dictionary © Farlex 2012

Agouti-Related Peptide

A peptide produced in the arcuate nucleus in the hypothalamus, which increases appetite (an action countered by leptin), but reduces the rate of metabolism and energy expenditure. It is increased in obese subjects.

Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.