advanced gastric cancer

Invasive adenocarcinoma of the stomach which extends beyond the submucosa.

Clinical findings
Peptic ulcer symptoms, anaemia, weight loss, haematemesis and symptoms of gastric outlet obstruction.

Management
Palliative surgical resection, surgical bypass (gastrojejunostomy), radiation therapy and endoscopic techniques; radical gastrectomy carries a rate of perioperative morbidity and no survival benefit.

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