acrocephalosyndactyly

[ak″ro-sef″ah-lo″sin-dak´tĭ-le]

any of a group of autosomal dominant disorders in which craniostenosis is associated with acrocephaly (conical deformity of the head) and syndactyly (webbed fingers and toes), sometimes occurring with additional anomalies. Type I is Apert's syndrome; type III is Chotzen's syndrome; and type V is Pfeiffer's syndrome.

ac·ro·ceph·a·lo·syn·dac·ty·ly (ACPS),

(ak'rō-sef'ă-lō-sin-dak'ti-lē),

A group of congenital syndromes characterized by craniosynostosis with abnormal head shape and cutaneous and/or bony syndactyly. There are several types with most types inherited as autosomal dominant. The phenotypes of types II and IV are not well defined.

[acrocephaly + G. syn, together, + daktylos, finger]

Farlex Partner Medical Dictionary © Farlex 2012

acrocephalosyndactyly

A family of autosomal dominant conditions caused by premature closure of cranial sutures resulting in a peaked head and facial dysmorphia.

Management
Surgery to correct skull and facial abnormalities.

Acrocephalosyndactyly
Type 1: Apert syndrome.
Type 2: Apert-Crouzon syndrome; both are regarded as part of the same condition MIM 101200.
Type 3: Chotzen or Saethre-Chotzen syndrome MIM 101400.
Type 5: Pfeiffer syndrome MIM 101600.

acrocephalosyndactyly

Pediatrics A family of AD conditions due to premature closure of cranial sutures resulting in a peaked head and facial dysmorphia Imaging Skull film Management Surgery to correct skull and facial abnormalities. See Bird face.

ac·ro·ceph·a·lo·syn·dac·tyly

(ak'rō-sef'ă-lō-sin-dak'ti-lē)

A group of congenital syndromes characterized by peaking of the cranium and fusion or webbing of fingers or digits.

[acrocephaly + G. syn, together, + daktylos, finger]