Patient discussion about methotrexate

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Q. Is methotrexate available in the United States as a treatment for fibromyalgia?

Last year I was diagnosed as fibromyalgia. I feel a lot of fatigue and stiffness. I came upon a website from where I read that rheumatoid arthritis causes those same symptoms and can be treated with methotrexate. After reading that, I purchased a half year supply of the drug over the counter in Mexico. It eliminated all of my symptoms. A month after my supply ran out, all the symptoms returned. Is methotrexate available in the United States as a treatment for fibromyalgia?
AYes fatigue and stiffness are some of the symptoms of fibromyalgia. Methotrexate is certainly available in the United States, but it is not approved for nor used as a treatment for fibromyalgia. It was originally developed to treat cancer and subsequently found to be very effective for a number of inflammatory disorders, such as RA and psoriasis. Because fibromyalgia is not an inflammatory disorder – that is, there is no identifiable inflammation in the muscles or joints in individuals with this condition – it is not clear why you responded to this drug. You should tell your physician about your response to methotrexate. It may be possible that you have an inflammatory disorder rather than – or in addition to – fibromyalgia.
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