A recent publication revealed that
Zyxin, a scaffold protein encoded by ZYX, was required in TGF-[beta] signaling pathway in response to hypoxia [77].
Song, "Association of resistance to avian coccidiosis with single nucleotide polymorphisms in the
zyxin gene," Poultry Science, vol.
As a component of focal adhesions, Testin interacts with the cytoskeletal protein such as
zyxin, talin, vasodilator-stimulated phosphoprotein, Mena, extractable nucler antigen (EVL), alphall-spectrin, actin and actin-related proteins 7A.
Zyxin binds alpha-actinin and the CRP protein and helps cell adhesion [24] and the cells used in this study expressed
Zyxin.
For example, the team found that in a 3-D environment, cells possessing the protein
zyxin would move in a random way, exploring their local environment.
On the one hand, mitochondria are crucial for cell motility via their interaction, mediated by the outer membrane protein
zyxin, with the actin cytoskeleton.
For EIA, we used the physiologic VASP binding partner
zyxin as a capture molecule.
"
Zyxin, axin, and Wiskott-Aldrich syndrome protein are adaptors that link the cadherin/catenin protein complex to the cytoskeleton at adherens junctions in the seminiferous epithelium of the rat testis," Journal of Andrology 25(2): 200-215.
Ajuba is novel group 3 LIM protein along with
zyxin, paxillin, trip6 and others.