Since the effects of
zinc acetate lozenges were consistent between the compared subgroups, the overall estimates for effect seem applicable over a wide range of common cold patients, according to researchers.
(2mmol, 0.396g) of 2,4-dinitrophenylhydrazine and (lmmol, 0.220g) of
Zinc acetate were weighed carefully into a mortar.
Pooling the three high dose (>75 mg/day)
zinc acetate trials gives a mean effect of 42% reduction in the duration of colds.
According to the company, Diphenhydramine hydrochloride is a topical analgesic and
zinc acetate is a skin protectorant, both of which are in the OTC monograph and can be sold as creams in a combination.
Furthermore, in the most recent trial on
zinc acetate lozenges, there were no significant differences between the zinc and placebo groups in the occurrence of adverse effects although the daily dose of zinc was 92 mg.
Three studies showed that daily doses of
zinc acetate higher than 75 mg shortened colds by an average 42%.
The consensus for stopping the common cold in its tracks - for adults - seems to suggest an upper limit of a cold remedy that provides in the realm of 40 mg of
zinc acetate per day, for a maximum of five days.
Analytical grade chemicals such as
zinc acetate ([C.sub.4][H.sub.6][O.sub.4]Zn.
But Zicam Cold Remedy products, which use propriety formulations of zinc gluconate and
zinc acetate as active ingredients, reduce the duration and severity of symptoms when taken within 24 to 48 hours of the first sign of a cold.
ABSTRACT : Two inorganic (zinc sulfate and zinc oxide) and three organic (
zinc acetate, zinc-methionine, and zinc-lysine) zinc sources were evaluated for their effects on the performance and carcass characteristics of broiler chicks.
Duration and severity of symptoms and levels of plasma interleukin-1 receptor antagonist, soluble tumor necrosis factor receptor, and adhesion molecules in patients with common cold treated with
zinc acetate. Journal of Infectious Diseases, 2008; 197(6): 795-802.