Woo, "Prophylactic alpha interferon treatment increases the therapeutic index of oncolytic
vesicular stomatitis virus virotherapy for advanced hepatocellular carcinoma in immune-competent rats," Journal of Virology, vol.
Blood-feeding behavior of
vesicular stomatitis virus infected Culicoides sonorensis (Diptera: Ceratopogonidae).
Evolution of fitness in experimental populations of
vesicular stomatitis virus.
The rVSV?G-LASV-GPC Vaccine is based on an attenuated strain of
vesicular stomatitis virus that has been modified to express a Lassa fever virus protein that plays an essential role in establishing virus infection.
The collaboration is aimed at jointly developing a new generation oncolytic virus therapy platform and to investigate the company's lead candidate VSV-GP (
Vesicular Stomatitis Virus (VSV) glycoprotein (GP)).
The experimental vaccine is based on a genetically modified and attenuated
vesicular stomatitis virus (VSV), a virus that mainly affects cattle.
Ebola vaccines are also well underway in preclinical research, through non-replicating viral vectors platforms (chimpanzee adenovirus Ad3), viral-vectored vaccines (
vesicular stomatitis virus, or modified vaccinia Ankara), recombinant adenovirus vector platform (Ad 26 & Ad 35), or adjuvanted virus-like particles.
They found that when the assembly of STAT1 chains was inhibited, type I interferons responsible for protecting against viruses such as
vesicular stomatitis virus were unaffected, whereas type II interferons, which protect against bacterial infections such as listeria, no longer functioned effectively.
(Profectus), a clinical stage biopharmaceutical company focused on the development of novel vaccine candidates for serious chronic infections, has entered into a research collaboration agreement with the PATH Malaria Vaccine Initiative (MVI) to conduct proof-of-concept study with its proprietary, recombinant
vesicular stomatitis virus (rVSV) vector technology as a preventative malaria vaccine.
It can also be used to quickly distinguish between FMD and
vesicular stomatitis, an animal disease with similar symptoms that occasionally crops up in the United States.