ty·phus vac·cine

a formaldehyde-inactivated suspension of Rickettsia prowazekii grown in embryonated eggs; effective against louse-borne (epidemic) typhus; primary immunization consists of two subcutaneous injections 4 or more weeks apart; booster doses are required every 6-12 months, as long as the possibility of exposure exists. A vaccine containing living rickettsiae of an attenuated strain of R. prowazekii has also been used.

Farlex Partner Medical Dictionary © Farlex 2012

typhus vaccine

An obsolete vaccine prepared from a sterile suspension of formalin-inactivated Rickettsia prowazekii grown in embryonated chicken eggs.

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References in periodicals archive

Later in 1944, Marinus was seconded to the Wellcome Research Laboratories of Tyburn, to head up the large-scale production of scrub typhus vaccine. This was in vivo cultivation of rickettsiae on a massive scale in cottontail rats, with harvesting of rickettsiae from infected rat lungs.

Marinus van den Ende

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