Genetic association studies of
tumour necrosis factor alpha and beta and
tumour necrosis factor receptor 1 and 2 polymorphisms across the clinical spectrum of multiple sclerosis.
Based on our data, we think miR-30d probably plays multiple roles, both in enhancing insulin production and in protecting cells from the inflammatory effects of
tumour necrosis factor," the biologist added.
Increased levels of cytokines including
tumour necrosis factor (TNF) alpha play an important role in the inflammatory process in Crohn's disease (CD).
Association between polymorphism of
tumour necrosis factor alpha-308 gene promoter and asthma: a meta-analysis.
Primary biliary cirrhosis shows association with genetic polymorphism of
tumour necrosis factor a promoter region.
However, some types of these molecules, such as
tumour necrosis factor (TNF) family cytokines, may play a dual role.
More specifically, FDA has approved ACTEMRA for the treatment of adult patients with moderately to severely active RA who have had an inadequate response to one or more
tumour necrosis factor (TNF) antagonist therapies.
Polymorphism at position -308 of the
tumour necrosis factor alpha gene and rheumatoid arthritis pharmacogenetics.
Role of
tumour necrosis factor in the enhanced sensitivity of mice to endotoxin after exposure to lead.
Polymorphisms in or near
tumour necrosis factor (TNF)-gene do not determine levels of endotoxin-induced TNF production.
Rattray, "
Tumour necrosis factor alpha induces rapid reduction in AMPA receptor-mediated calcium entry in motor neurones by increasing cell surface expression of the GluR2 subunit: relevance to neurodegeneration," Journal of Neurochemistry, vol.