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A total of 93 subjects with classical myeloproliferative neoplasms were evaluated in the study, 33(35%) of them were polycythaemia vera, 36 (39%) were essential thrombocythaemia and 24 (26%) were having idiopathic myelofibrosis.

FREQUENCY OF JANUS ASSOCIATED KINASE 2 (JAK2) MUTATION IN PATIENTS OF BCR-ABL NEGATIVE MYELOPROLIFERATIVE NEOPLASMS

AESSENTIAL thrombocythaemia is a rare condition in which cell fragments in the blood (platelets, which help clotting) increase in numbers to over 1000 x 109 /L - around three times higher than normal.

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This report provides comprehensive information on the therapeutic development for Thrombocythaemia Myelofibrosis, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases.

Recent Study: Thrombocythaemia Myelofibrosis - Pipeline Review, H1 2015

[USPRwire, Mon Dec 08 2014] Global Markets Direct's, 'Thrombocythaemia Myelofibrosis - Pipeline Review, H2 2014', provides an overview of the Thrombocythaemia Myelofibrosis's therapeutic pipeline.

Report Published: "Thrombocythaemia Myelofibrosis - Pipeline Review, H2 2014"

Histomorphometry of bone marrow biopsies in chronic myeloproliferative disorders with associated thrombocytosis-features of significance for the diagnosis of primary (essential) thrombocythaemia. Virchows Arch A Pathol Anat Histopathol.

Megakaryocytic Morphology and Clinical Parameters in Essential Thrombocythemia, Polycythemia Vera, and Primary Myelofibrosis With and Without JAK2 V617F

Fischer T, Kirkpatrick The Incidence of Myelofibrosis in Essential Thrombocythaemia, Polycythaemia vera and Chronic Idiopathic Myelofibrosis: A Retrospective Evaluation of Sequential Bone Marrow Biopsies.

The association between JAK2V617F mutation and bone marrow fibrosis at diagnosis in patients with philadelphia-negative chronic myeloproliferative neoplasms / Philadelphia Negatif kronik Miyeloproliferatif Neoplazili Hastalarin Tanisinda JAK2V617F mutasyonu ile Kemik Iligindeki Fibrozun Iliskisi

Serum erythropoietin values in erythrocytoses and in primary thrombocythaemia. Br J Haematol 2002;117:47-53.

Serum erythropoietin measured by chemiluminescent immunometric assay: an accurate diagnostic test for absolute erythrocytosis

Migrating emboli of retinal arteries in thrombocythaemia. Br J Ophthalmol 1969;53:279-81.

Central retinal artery occlusion as the presenting sign of essential thrombocythemia / Eansiyel trombositeminin basvuru belirtisi olarak santral retinal arter tikanikligi

Increased risk for vascular complications in PRV-1 positive patients with essential thrombocythaemia. Br J Haematol 2003;123:513-6.

Comparison of methods for polycythemia rubra vera-1 mRNA quantification in whole-blood leukocytes and purified granulocytes

Thrombosis and haemorrhage in polycythaemia vera and essential thrombocythaemia. Br J Haematol 2005;128:275-90.

Enhanced platelet adhesion in essential thrombocythemia after in vitro activation / In vitro aktivasyon sonrasi Esansiyel trombositemide yuksek platelet adezyonu

Impact of endogenous thrombopoietin levels on the differential diagnosis of essential thrombocythaemia and reactive thrombocytosis.

Is the thrombopoietin assay useful for differential diagnosis of thrombocytopenia? Analysis of a cohort of 160 patients with thrombocytopenia and defined platelet life span

Clonal analysis of haematopoietic cells in essential thrombocythaemia. Br J H aem atol 1995;90:131-7.

X-Chromosome inactivation in healthy females: incidence of excessive lyonization with age and comparison of assays involving DNA methylation and transcript polymorphisms