Thiamine pyrophosphate
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Thiamine pyrophosphate (TPP)
The coenzyme containing thiamine that is essential in converting glucose to energy.
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.
References in periodicals archive
This principle of megadoses of vitamins appears to be an important fact in the modern era and our experience has shown repeatedly that a prolonged deficiency of thiamine cannot be addressed by physiological RDA doses in patients with an abnormal
thiamine pyrophosphate effect (TPPE).
These findings are supported by a previous study of non-enzymatic glycosylation of proteins and glycation inhibition by thiamine and other inhibitors.18 Our results are in conformity with a previous report19 claiming that
thiamine pyrophosphate and pyridoxamine inhibit the formation of antigenic AGEs compared with aminoguanidine.
Thiamine and
thiamine pyrophosphate, both showed protective effects albeit to different extents.
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