Somatic cell nuclear transfer in its first and second decades: successes, setbacks, paradoxes and perspectives.
somatic cell nuclear transfer in the sheep induces placental defects that likely precede fetal demise.
Somatic cell nuclear transfer is also known as therapeutic cloning.
The controversy surrounds a bill that seeks to outlaw therapeutic cloning, also known as
somatic cell nuclear transfer. In therapeutic cloning, the nucleus of a woman's unfertilized egg is removed and replaced with the nucleus of another cell from a human body.
Canada, under the jurisdiction of the Assisted Human Reproduction Agency (within the Canadian Institutes for Health Research), allows use of the excess embryos from in vitro fertilization to be used for embryonic stem cell derivation, but does not yet allow
somatic cell nuclear transfer. Sweden allows
somatic cell nuclear transfer research.
The third technique, also known as "cloning," is to derive embryonic stem cells via
somatic cell nuclear transfer. A complete set of genetic material (all 46 chromosomes that reside within the nucleus of a somatic cell) is transferred into an enucleated female egg (which normally contains half the total complement of chromosomes).
to extend the derivation of embryonic stem cell lines beyond spare IVF embryos to embryos derived through
somatic cell nuclear transfer, or cloning techniques.
There are different techniques by which cloning might proceed (66) but the only kind of cloning currently considered viable is known as "
somatic cell nuclear transfer." (67) This procedure involves removing the nucleus from an oocyte (of person 1), substituting the nucleus from a somatic (or "body" or non-germ) cell from someone else (person 2), and stimulating the cell with an electrical charge.
The AMA came out in favor of using
somatic cell nuclear transfer to develop stem cells for research purposes.
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Somatic cell nuclear transfer is about saving and improving lives.
The practical effect of
somatic cell nuclear transfer is the embryonic development of a second organism containing the genetic code of the first organism.
The ability to reproduce individuals through
somatic cell nuclear transfer has been accomplished in at least five species, the latest being that of the cat.