skin/hair/eye pigmentation type 2

A genetic variation of hair, eye and skin pigmentation typical of populations living further from the equator (e.g., northern Europeans). Individuals with SHEP2 often have partial loss-of-function mutations of MC1R, which encodes melanocortin 1 receptor, and are characterised by fair skin, blonde or red hair, poor tanning and increased risk of skin cancer due to increased susceptibility to UV-light-induced skin damage.

All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for informational purposes only. This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional.