Medical

seroreversion

Also found in: Wikipedia.

seroreversion

 [sēr″o-re-ver´zhun]
spontaneous or induced conversion from a seropositive to a seronegative state.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

se·ro·re·ver·sion

(sē'rō-rē-ver'zhŭn),
A loss in serologic reactivity; may be spontaneous or in response to therapy.
Farlex Partner Medical Dictionary © Farlex 2012

seroreversion

Immunology A change from seropositivity–production of antibodies to a particular antigen or pathogen, to seronegativity–nonproduction of antibodies. See Seronegativity.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
References in periodicals archive
Seroreversion of serological tests for syphilis in the disabled community in Mazandaran province of Iran.
Pre-emptive therapy is based upon monitoring HBsAg and/or HBVDNA levels every 1-3 months during and after chemotherapy/immunosuppressive therapy, and starting potent NA treatment when HBV DNA is detectable or HBsAg seroreversion (1,2,14,19).
West Nile Seroreversion and the Influence of Herd Immunity on Disease Risk in a LongTerm Study of Free-Ranging Birds [master's thesis].
Most cases of HBV reactivation in the literature describe HBsAg seroreversion that leads to either low-level viremia without ALT elevation or more significant reactivation with high-level viremia and ongoing immune-mediated liver injury with ALT elevation.
Delayed seroreversion at >18 months of age in HIV-uninfected infants has been described in Malawi, Vietnam, Brazil and the USA.
The limitations include increased rate of negative serology test in both primary and secondary syphilis, increase false-negative non- treponemal antibody test due to prozone reaction, high rate of serological failure to clear non-trepone- mal antibody test after treatment and seroreversion to negative of specific treponemal antibody tests following treatment.7
Seroreversion in subjects receiving antiretroviral therapy during acute/early HIV infection.
Moreover, late seroconversion, persistent seronegativity, and seroreversion of IgG against HEV have been reported for severely immunocompromized patients, including some infected with HIV (3-5), which brings up the question as to whether prevalence of IgG against HEV is underestimated among severely immunocompromised persons infected with HIV.
One of the cases displayed transient initial HBe seroconversion at 1 week, followed by seroreversion to positive HBeAg and negative HBeAb at week 3, which was subsequently followed by another seroconversion at week 7 which, this time, was maintained over the course of the following month, when the patient kept up with follow-up visits.
INFLUENCE OF HIV ON THE COURSE OF HEPATITIS B VIRUS INFECTION * Higher rates of chronicity after acute HBV infection * Decreased rates of spontaneous HBsAg and HBeAg seroconversion * Increased rates of HBV DNA replication * More severe liver disease, with increased rates of cirrhosis and hepatocellular carcinoma * Increased rates of liver-related mortality * Increased rates of occult HBV infection * Increased rate of reactivation and seroreversion with decreasing CD4 counts * Increase risk of HBV flare after starting HAART due to HBV-immune reconstitution inflammatory syndrome (HBV-IRIS) TABLE II.
Copyright © 2003-2025 Farlex, Inc Disclaimer
All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for informational purposes only. This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional.