sarcosine dehydrogenase
sar·co·sine de·hy·dro·gen·ase
[MIM*604455] an enzyme that cleaves sarcosine using some acceptor to produce glycine, formaldehyde, and a reduced acceptor molecule; a deficiency of this enzyme will result in sarcosinemia.
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References in periodicals archive
Sarcosine in the presence of an enzyme,
Sarcosine dehydrogenase is converted into glycine, while another enzyme, Glycine - N- methyl transferase generates Sarcosine by degradation of glycine.
DMG is converted into sarcosine and sarcosine is converted into glycine by two oxidative demethylation steps mediated by DMG dehydrogenase (DMGDH; EC 1.5.99.2) and
sarcosine dehydrogenase (EC 1.5.99.1), respectively.
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