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santonin

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san·to·nin

(san'tō-nin),
The inner anhydride or lactone of santoninic acid, obtained from santonica, the unexpanded flower heads of Artemisia cina and other species of Artemisia (family Compositae); has been used to effect expulsion of roundworms (Ascaris lumbricoides), and in the treatment of urinary incontinence.
[G. santonikon, wormwood]
Farlex Partner Medical Dictionary © Farlex 2012

santonin

(săn′tə-nĭn)
n.
A colorless crystalline compound, C15H18O3, obtained from species of wormwood, especially santonica, and formerly used as an anthelmintic.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
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References in periodicals archive
Our aim was to synthesize the new chemical entities derived from santonin with oxadiazole moiety and to evaluate them for the antimicrobial activities.
Santoninic acid is quite unstable and relactonized back to santonin due to its kinetic nature.
Shah, Studies on the Antiinflammatory, Antipyretic and Analgesic Activities of Santonin. Jap.
Furlani, Synthesis and In Vitro Cytotoxic Activity of Semisynthetic Derivatives in the Santonin Series.
Biology-Oriented Syntheses (BIOS) of Novel Santonic-1,3,4-oxadiazole Derivatives under Microwave-Irradiation and their Antimicrobial Activity
Keywords: Polygonatum verticillatum Rhizome Extract Lipoxygenase Urease Santonin.
Based on various spectroscopic techniques the structure of compound 1 was assigned as (6S7S10S11S)-41011-trimethyl-78910- tetrahydronaphtho[1612-b]furan-312(6H11H)-dione (santonin) which is a known compound [19 20].
Table-3: In vitro quantitative inhibition of urease and lipoxygenase by Santonin.
Lipoxygenase and Urease Inhibition of Extracts of Polygonatum verticillatum Rhizome: Augmented by its Isolated Compound Santonin
The activity of 1 and 2 was more potent than Santonin and p-anisaldehyde whose [ED.sub.50] against C.
Tribulosin and [beta]-sitosterol-D-glucoside, the anthelmintic principles of Tribulus terrestris
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