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ribonucleic acid

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ribonucleic acid

 (RNA) [ri″bo-noo-kle´ik]
a nucleic acid that is present in all living cells and controls cellular protein synthesis; it replaces deoxyribonucleic acid (DNA) as a carrier of genetic codes in some viruses. RNA is similar in composition to DNA with two exceptions: the sugar in RNA is ribose, as opposed to the deoxyribose of DNA, and in RNA the pyrimidine uracil is found instead of the thymine of DNA. The structure of RNA varies from helical to uncoiled strands of varying lengths, depending on the number of nucleotide units forming the strand. This variance in structure is evident in the different types of RNA. For example, transfer RNA (tRNA) contains only about 75 nucleotide units, while other types may contain thousands of units.



Messenger RNA (mRNA) receives its name from its function of carrying the genetic code from the nucleus of the cell to the cytoplasm, where most cellular functions take place. The transfer of the genetic code from DNA to mRNA is called transcription. Molecules of mRNA migrate to the ribosomes, where the manufacture of proteins occurs. The strands of RNA contain codons, some of which signal when formation of a particular protein should stop and the formation of another should start.

Transfer RNA (tRNA) brings about the transfer of specific amino acid molecules to protein molecules during the synthesis of proteins. Each of the 20 common amino acids found in protein molecules has a corresponding type of transfer RNA. Thus, a specific tRNA carries the appropriate amino acid to its appropriate place in the chain of the protein molecule being synthesized.

Ribosomal RNA (rRNA) is so called because it is found in the ribosomes. It is the most abundant type of RNA and in some way affects the linking of amino acids into protein molecules.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

ri·bo·nu·cle·ic ac·id (RNA),

(rī'bō-nū-klē'ik as'id),
A macromolecule consisting of ribonucleoside residues connected by phosphate from the 3'-hydroxyl of one to the 5'-hydroxyl of the next nucleoside. RNA is found in all cells, in both nuclei and cytoplasm and in particulate and nonparticulate form, and also in many viruses; polynucleotides made in vitro are generally called such. Various RNA fractions are identified by location, form, or function.
Farlex Partner Medical Dictionary © Farlex 2012

ribonucleic acid

(rī′bō-no͞o-klē′ĭk, -klā′-, -nyo͞o-)
n.
See RNA.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

ri·bo·nu·cle·ic ac·id

(RNA) (rī'bō-nū-klē'ik as'id)
A macromolecule consisting of ribonucleoside residues connected by phosphate bonds, concerned in the control of cellular chemical processes, especially protein synthesis. RNA is found in all cells, in both nuclei and cytoplasm, and in many viruses.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

ribonucleic acid

See RNA.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

ribonucleic acid

see RNA.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005

ri·bo·nu·cle·ic ac·id

(RNA) (rī'bō-nū-klē'ik as'id)
Macromolecule consisting of ribonucleoside residues connected by phosphate from the 3'-hydroxyl of one to the 5'-hydroxyl of the next nucleoside; found in all cells, in both nuclei and cytoplasm and in particulate and nonparticulate form, and also in many viruses. Various RNA fractions are identified by location, form, or function.
Medical Dictionary for the Dental Professions © Farlex 2012
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References in periodicals archive
RNA - Ribonucleic acid, companion substance to DNA in the chemistry of heredity.
Quantitative reverse transcription polymerase chain reaction was used to find the differences of micro ribonucleic acid 34-a between metastatic neuroblastoma and primary tumours.
Specifically, the RNA molecules of the present invention are double-stranded ribonucleic acid molecules (dsRNA).
Factors associated with the development of liver disease in these patients included testing positive for HCV ribonucleic acid, age greater than 39 years at the time of infection, and the number of years since transfusion.
Tests have shown a significant increase in the synthesis activity of ribonucleic acid, a function of the liver, leading researchers to conclude that the bone marrow cells were transforming into liver cells, they said.
Wheat streak mosaic virus (WSMV) is little more than a genetic snippet of ribonucleic acid. But for the Northern Great Plains, outbreaks of this rogue RNA molecule in winter wheat can mean big losses.
Now, Taubenberger hopes he can map sequences of the virus's RNA (ribonucleic acid), the genetic material of many viruses.
Ribonuclease, which catalyzes ribonucleic acid's breakdown into smaller fragments, was the first enzyme to be synthesized.
These are two novel liquid biopsy workflows for cancer research designed to enable non-invasive extraction and purification of ribonucleic acid.
The collaboration combines Origenis' capabilities in compound design, chemical synthesis, and screening with Expansion's field-leading expertise in the discovery and development of small molecules interacting with ribonucleic acid.
Summary: Philadelphia, [USA] June 23 (ANI): Editing and blocking the viral Ribonucleic acid (RNA) strands can slow down the replication of Influenza A (Flu A) virus.
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