racemization

[ra″sĕ-mĭ-za´shun]

the transformation of one-half of the molecules of an optically active compound into molecules that possess exactly the opposite (mirror-image) configuration, with complete loss of rotatory power because of the statistical balance between equal numbers of dextrorotatory and levorotatory molecules.

ra·ce·mi·za·tion

(rā'sē-mi-zā'shŭn, rās-mi-),

Partial conversion of one enantiomorph into another (as an l-amino acid to the corresponding d-amino acid) so that the specific optical rotation is decreased, or even reduced to zero, in the resulting mixture.

Farlex Partner Medical Dictionary © Farlex 2012

ra·ce·mi·za·tion

(rā'sĕ-mī-zā'shŭn)

Partial conversion of one enantiomorph into another (as an l-amino acid to the corresponding d-amino acid) so that the specific optic rotation is decreased, or even reduced to zero, in the resulting mixture.

Medical Dictionary for the Health Professions and Nursing © Farlex 2012

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References in periodicals archive

The process of cationic ROP can produce low-molecular-weight poly lactic acid while anionic ROP process can lead to racemization [15].

Metabolic Engineered Biocatalyst: A Solution for PLA Based Problems

Age estimation based on aspartic acid racemization in human sclera.

Morphology and Volume of Maxillary Canine Pulp Cavity for Individual Age Estimation in Forensic Dentistry/Morfologia y Volumen de la Cavidad de Pulpa del Canino Maxilar para la Estimacion de la Edad Individual en Odontologia Forense

Racemization is a chemical process that converts pure enantiomers

Forensic individual age estimation with DNA: From initial approaches to methylation tests

The melanoidin pigment, formed during Maillard reaction, might be connected with racemization of amino acids (Kim and Lee, 2008).

Black garlic: transformation effects, characterization and consumer purchase intention

This 23-chapter book explores mechanisms linking aging, disease, and biological age estimation, focusing on four of the hallmarks of aging--aspartic acid racemization, advanced glycation endproducts, telomere shortening, and mitochondrial DNA mutations--and their role in aging and diseases and their application in age-at-death estimation in forensic sciences.

Mechanisms Linking Aging, Diseases and Biological Age Estimation

For example, measuring the racemization of aspartic acid in collagen from human cartilage and skin, a half-life of 117 years for cartilage collagen and 14.8 years for skin collagen was described [56], whereas in rats a collagen turnover time of 30-150 days was described [57].

Cardiac Function Remains Impaired Despite Reversible Cardiac Remodeling after Acute Experimental Viral Myocarditis

Since racemization is not possible during the reaction, this method allows the preparation of enantiopure 1,2,3-benzotriazinones in excellent yields.

A Novel Synthesis of 1,2,3-Benzotriazinones from 2-(o-Aminophenyl)oxazolines

Many of these are chiral molecules that can exist in plants in different enantiomeric forms, such as the pepper aroma compound linalool [82], which occurs naturally in one enantiomeric form but experiences racemization during postharvest treatment [75, 83].

The Chilhuacle Chili (Capsicum annuum L.) in Mexico: Description of the Variety, Its Cultivation, and Uses

Nishida, "Quantitative evaluation of photodegradation and racemization of poly(l-lactic acid) under UV-C irradiation," Polymer Degradation and Stability, vol.

Development and Characterization of Photoinduced Acrylamide-Grafted Polylactide Films for Biomedical Applications

Thus, no detectable racemization took place under the conditions of the Pd-catalyzed vinylation.

Catalytic enantioselective synthesis of chiral organic compounds of ultra-high purity of >99% ee