KLK3

A gene on chromosome 19q13.41 that encodes a serine protease with diverse physiological functions, which may also have a role in carcinogenesis. KLK3 hydrolyses semenogelin-1, leading to the liquefaction of the seminal coagulum.

PSA (Prostate specific antigen)

A tumor marker associated with prostate cancer.

Mentioned in: Tumor Markers

Patient discussion about Prostate specific antigen

Q. Would kidney stones affect a PSA reading? Would drinking lots of grapefruit juice affect a PSA reading? My husband's PSA reading jumped from a 4.2 to a 17 in @ 2 years' time. How can that be? This man takes all sorts of supplements and really watches his diet. He also takes good care of his body, and does NOT look or act 68.

A. You should get your parathyroid gland checked out. Your calcium level might be causing the kidney stones.

Q. Rising PSA to 10 with two negative biospies? Expect cancer? 67 yrs old in good health otherwise.

A. High values don't always mean it's cancer. At 67 years old, you're prostate is most likely enlarging, resulting in the higher PSA results. And after two negative biopsies, it sounds like you're in the clear. Like Brandon said though, keep up with your regular check ups.
Source: http://www.northshore.org/healthresources/encyclopedia/encyclopedia.aspx?Version=Q3_08&DocumentHwid=hw5522&ViewHwid=hw5548

More discussions about Prostate specific antigen

This content is provided by iMedix and is subject to iMedix Terms. The Questions and Answers are not endorsed or recommended and are made available by patients, not doctors.

Mentioned in

References in periodicals archive

Nomogram for prediction of prostate cancer with serum prostate specific antigen less than 10 ng/mL.

CAVEATS OF PROSTATE CANCER DIAGNOSIS: DIAGNOSTIC UTILITY STUDY OF DIGITAL RECTAL EXAMINATION, PROSTATE VOLUME AND PROSTATE SPECIFIC ANTIGEN

Role of digital rectal examination and prostate specific antigen in detecting carcinoma prostate.

FREE/TOTAL PROSTATE SPECIFIC ANTIGEN RATIO AS PREDICTOR FOR PROSTATE CARCINOMA

Prostate specific antigen best practice statement: 2009 update.

Clinicopathological correlation of serum prostate specific antigen levels in patients of prostatomegaly in a tertiary care hospital

Histopathological study of transrectal ultrasound guided biopsies of prostate in patients with raised serum prostate specific antigen. NHL Journal of Medical Sciences 2015;4(1):70-4.

Utility of prostate specific antigen in the diagnosis of various prostatic lesions

Serum index test %[-2]proPSA and prostate health index are more accurate than prostate specific antigen and %fPSA in predicting a positive repeat prostate biopsy.

Comparative assessment of urinary prostate cancer antigen 3 and TMPRSS2:ERG gene fusion with the serum [-2]proprostate-specific antigen-based prostate health index for detection of prostate cancer

Patients having suspicion of malignancy either on history or rectal examination were advised to test for prostate specific antigen and those with values over 10 ng/dl were excluded from the study.

Frequency of Malignancy in Clinically Benign Open Transvesical Prostatectomy- A study of 100 cases

Effect of digital rectal examination and needle biopsy on serum total and percentage of free prostate specific antigen levels.

The PSA controversy: part I

Age, free/total prostate specific antigen (fPSA/tPSA), and prostate volume in benign prostate hyperplasia (BPH) patients diagnosed with and without chronic prostatitis.

Incidental detection of asymptomatic chronic prostatitis and benign prostate hyperplasia in patients with high serum PSA levels: a preliminary retrospective study / Yuksek serum PSA degerli hastalarda rastlantisal tespit edilen asemptomatik kronik prostatit ye benign prostat hiperplazi: Retrospektif bir on calisma

Prostate specific antigen density: A means of distinguishing benign prostatic hypertrophy and prostate cancer.

Evaluation of diagnostic accuracy of different biomarkers for prostate cancer

Key words: prostate specific antigen, prostate carcinoma, unknown primary cancer

Serial serum prostate specific antigen measurements over time in a patient presenting with a metastatic adenocarcinoma of unknown origin

It helps men decide whether to take a prostate specific antigen (PSA) test, which measures the level of PSA in the blood.

Prostate cancer website for men

SAN FRANCISCO -- A soy-based nutritional supplement delayed the rise in prostate specific antigen levels after treatment for prostate cancer in a double blind, placebo-controlled pilot study of 49 patients, Dr.

Use of soy-based supplement slows increase in PSA levels; post-prostate cancer trial