Adjuvant
procarbazine, lomustine, and vincristine improves progression-free survival but not overall survival in newly diagnosed anaplastic oligodendrogliomas and oligoastrocytomas: a randomized European Organisation for Research and Treatment of Cancer phase III trial.
Procarbazine containing regimes result in prolonged azoospermia in the vast majority of patients.
Treatment for Hodgkin's lymphoma with MVPP (mechlorethamine, vinblastine,
procarbazine and prednisolone), MOPP (mechlorethamine, vincristine,
procarbazine and prednisolone) or ChIVPP (chlorambucil, vinblastine,
procarbazine and prednisolone) resulted in permanent ovarian failure in 19 - 63% of cases.
The researchers compared various chemotherapy regimens and IFRT doses and found that outcomes were similar when 30 Gy of IFRT was combined with either four cycles of ABVD (doxorubicine, bleomycin, vinblastine, and dacarbazine) or four cycles of BEACOPP (bleomycin, etoposide, doxorubicin, cyclophosphamide, vincristine,
procarbazine, prednisone).
Effects of prenatal
procarbazine administration on intrauterine development in rats.
The nodes were irradiated and she also received a course of
procarbazine hydrochloride.
Plants have a long history of use in the treatment of cancer providing some of the currently used effective anticancer agents such as vinblastine, vincristine, mechlorethamine, prednisone,
procarbazine, etoposide, teniposide, paclitaxel, bleomycin, cisplatin and taxanes (DeVita et al.
Phase I study of temozolamide (TMZ) combined with
procarbazine (PCB) in patients with gliomas.
He underwent mantle field radiation therapy and four cycles of MOPP (mechlorethamine, vincristine,
procarbazine, and prednisone) chemotherapy.
Treatment protocol: Most patients were treated with chemotherapy alone, alternating 4 cycles of COPP (cyclophosphamide, vincristine,
procarbazine and prednisolone) with 4 cycles of ABVD (doxorubicin, bleomycin, vinblastine and dacarbazine).
The drug that started it all, Mustargen, became a key element in the revolutionary MOPP (Mustargen, Oncovin,
procarbazine, and prednisone) combination chemotherapy regimen pioneered by Dr.