These differences can be related to the differences of neuronal density between the segments of each study, and also to the fact that not all myenteric neurons are myosin V positive while
polyribosomes of all neurons are stained by Giemsa technique.
Use of this gradient allowed for analysis of the "native" state of the
polyribosome size structure and for the determination of the number of ribosomes attached to, and actively translating on, mRNA transcripts.
They also exhibit elongated mitochondria with few crests, Golgi apparatus and large amounts of the smooth endoplasmic reticulum, ribosomes and free
polyribosomes (Fig.
Protein synthesis,
polyribosomes, and peptide elongation in early development of Strongylocentrotus purpuratus.
La Regina et al., "Increased cytoplasmic TDP-43 reduces global protein synthesis by interacting with RACK1 on
polyribosomes," Human Molecular Genetics, vol.
Polypeptides called procollagen chains are produced on
polyribosomes bound to membranes of RER and translocated into the cisternae and the signal peptide is clipped off.
NR0B1 (DAX1) protein binds mRNAs associated with
polyribosomes and regulates other gene expressions on the posttranscriptional level [9].
Association of the mouse infertility factor DAZL1 with actively translating
polyribosomes. Biol Reprod 2000;62(6): 1655-1660.
Richter, "Human let7a miRNA blocks protein production on actively translating
polyribosomes," Nature Structural and Molecular Biology, vol.
The results of the TEM showed that the adipocytes in the newly formed tissue were mature and had a well-developed nucleolus, a cytoplasm rich in ribosomes and
polyribosomes, glycogen clusters, small lipid droplets, and large, dense mitochondria with variable amounts of cristae.
This would lead to the dissembly of
polyribosomes (Lin and Glazer, 1981), incomplete methylation (Almstedt et al., 2010) and acceptor function of transfer RNA (Daskalakis et al., 2002).
These virus-like 30 ncRNAs are induced by ischemia and paradoxically bound to
polyribosomes, although they are not translated.