The "Microscopic
Polyangiitis (MPA) - Pipeline Review, H1 2019" drug pipelines has been added to ResearchAndMarkets.com's offering.
(10) There is a clear absence, however, of systemic diseases such as granulomatosis with
polyangiitis, Churg-Strauss syndrome, sarcoidosis, Sjogren syndrome, and infectious granulomatosis.
Imaging features suggested the possibility of a primary lung malignancy, organising pneumonia, granulomatosis with
polyangiitis, sarcoidosis or lymphoma.
Performance evaluation of three assays for the detection of PR3-ANCA in granulomatosis with
polyangiitis in daily practice.
Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is referred as a subgroup of small vessel vasculitis characterized by immune depositions and the presence of ANCAs and includes microscopic
polyangiitis (MPA), granulomatosis with
polyangiitis (GPA), and eosinophilic GPA (EGPA).
Eosinophilic granulomatosis with
polyangiitis or Churg--Strauss syndrome (CSS) is a systemic vasculitis characterized by bronchial asthma, hypereosinophilia, and systemic vasculitis.
It is seen in PAN, microscopic
polyangiitis, Wegener's granulomatosis, Churg-Strauss syndrome, and secondary vasculitis due to rheumatoid arthritis or Sjogren's syndrome.
(2) showed that serum-induced fibroblast proliferation in vitro was highly increased in microscopic
polyangiitis with pulmonary fibrosis compared to that without it, probably through oxidative stress, suggesting the potential of MPO-ANCA to trigger the fibrotic process.
Different characteristics were compared between the three groups of AAV; GPA (Granulomatosis with
polyangiitis), MPA (Microscopic
polyangiitis) and EGPA (Eosinophilic granulomatosis with
polyangiitis).
Rituximab is indicated for non-Hodgkin's lymphoma (NHL), chronic lymphocytic leukemia (CLL; in combination with chemotherapy), rheumatoid arthritis (RA; in combination with methotrexate), and granulomatosis with
polyangiitis and microscopic
polyangiitis (in combination with glucocorticoids) [20, 21].