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plasmin

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plasmin

 [plaz´min]
the active principle of the fibrinolytic or clot-lysing system, a proteolytic enzyme with a high specificity for fibrin and the particular ability to dissolve formed fibrin clots.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

plas·min

(plaz'min),
A serine proteinase catalyzing the hydrolysis of peptides and of esters of l-arginine and l-lysine and converting fibrin to soluble products; occurs in plasma as the precursor plasminogen (profibrinolysin) and is activated to plasmin by organic solvents, which remove an inhibitor, and by streptokinase, trypsin, and plasminogen activator, all cleaving a single arginyl-valyl bond; plasmin is responsible for the dissolution of blood clots.
Synonym(s): fibrinase (2) , fibrinolysin
Farlex Partner Medical Dictionary © Farlex 2012

plasmin

(plăz′mĭn)
n.
A proteolytic enzyme that is formed from plasminogen in blood plasma and dissolves the fibrin in blood clots. Also called fibrinolysin.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

plasmin

A proteolytic enzyme formed from plasminogen that lyses blood clots; plasmin exists in free and bound–fibrin-adsorbed forms; the former is destroyed as it is formed by antiplasmins, the latter acts as a serine endopeptidase to solubilize fibrin clots; it hydrolyzes lysine and arginine bonds in certain proteins–eg, fibrinogen, coagulation factors V and VII. See tPA.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

plas·min

(plaz'min)
An enzyme hydrolyzing peptides and esters of l-arginine and l-lysine, and converting fibrin to soluble products; responsible for the dissolution of blood clots.
Synonym(s): fibrinase (2) , fibrinolysin.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

plasmin

A protein-splitting enzyme in the blood that dissolves FIBRIN clots.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

plas·min

(plaz'min)
An enzyme responsible for the dissolution of blood clots.
Synonym(s): fibrinase (2) , fibrinolysin.
Medical Dictionary for the Dental Professions © Farlex 2012
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References in periodicals archive
The members of the plasminogen activation system and the mechanism of plasminogen activation: Binding of pro-uPA to its specific receptor, uPAR, causes the conversion of plasminogen into plasmin, which is achieved by proteolytic cleavage.
Relevance of the plasminogen activation system in the pathogenesis and progression of gastric cancer
Omasu et al., "Glomerular plasminlike activity in relation to nephritis-associated plasmin receptor in acute poststreptococcal glomerulonephritis," Journal of the American Society of Nephrology, vol.
De Novo Postinfectious Glomerulonephritis Secondary to Nephritogenic Streptococci as the Cause of Transplant Acute Kidney Injury: A Case Report and Review of the Literature
With the recent clinical introduction of ocriplasmin (microplasmin/Jetrea; ThromboGenics, Iselin, NJ) which is a recombinant truncated version of plasmin approved by the US Food and Drug Administration for the treatment of symptomatic vitreomacular traction, one would expect a better outcome of enzyme-assisted PVD in pediatric cases of TMH [57].
Current Management of Traumatic Macular Holes
Plasmin is a serine proteinase which not only acts on fibrin degradation leading to clot dissolution but also activates MMPs, growth factors, and proteinase-activated receptors ([PAR.sub.1]).
The Role of Proteinase-Activated Receptors 1 and 2 in the Regulation of Periodontal Tissue Metabolism and Disease
A lumbar puncture was then performed which prompted the performance of a rapid plasmin reagent (RPR).
Revisiting an old foe: the face of psychosis in neurosyphilis
2, pancreatic trypsin efficiently activated the infectivity of almost all strains, except IAV WSN/33(H1N1), and mini- and micro-plasmin (which are degradation products of plasmin found in inflammatory loci) also activated all strains though less efficiently than trypsin.
Influenza virus pathogenicity regulated by host cellular proteases, cytokines and metabolites, and its therapeutic options
The increase in proteolytic activity is associated with higher activity of plasmin in udders of deteriorating health (Albenzio et al., 2004).
THE EFFECT OF BREED, -LACTOGLOBULIN VARIANTS AND SOMATIC CELL COUNT ON YIELD, CHEMICAL COMPONENTS AND WHEY PROTEIN COMPOSITION IN MILK OF NON-DAIRY SHEEP
The somatic cells ally themselves with heat-resistant enzymes in the milk called plasmin, which can degrade proteins in a similar way to bacterial enzymes.
When milk quality goes wrong
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