placental site trophoblastic tumor
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pla·cen·tal site troph·o·blas·tic tu·mor
a tumor usually arising in the uterus of parous women during reproductive years. Histologically, the tumor consists of a predominance of intermediate trophoblastic cells with fibrinoid material and vascular invasion.
Farlex Partner Medical Dictionary © Farlex 2012
placental site trophoblastic tumor
Gynecologic pathology
A rare uterine neoplasm of gestational tissue of reproductive age ♀, presenting as a 'missed' abortion, which ranges from microscopic to massive and from 'timid' to highly aggressive that actively secretes human placental lactogen Prognosis 10% mortalityMcGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
References in periodicals archive
Placental site trophoblastic tumor is a space-occupying lesion involving endomyometrium, and patients usually present with vaginal bleeding or amenorrhea with mild elevation of serum hCG months or years after full-term pregnancy or abortion.
Abbreviations: ADAMTS, a disintegrin and metalloproteinase with thrombospondin motifs; PSTTs,
placental site trophoblastic tumors (original magnifications X400).
The diagnosis of hydatidiform mole is clinically important because of its potential to give rise to persistent gestational trophoblastic disease including invasive mole, choriocarcinoma and
placental site trophoblastic tumors. Furthermore, the distinction between complete and partial mole is also significant.8
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