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pOH

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pOH

The negative decadic logarithm of the OH- concentration (in moles per liter).
Farlex Partner Medical Dictionary © Farlex 2012

GNAS

A locus on chromosome 20q13.3 that has a highly complex imprinted expression pattern, giving rise to maternally, paternally and biallelically expressed transcripts derived from four alternative promoters and 5' exons. Some transcripts have a differentially methylated region (DMR) at their 5' exons. This DMR is commonly found in imprinted genes and correlates with transcript expression; one transcript produced from this locus and the antisense transcript are paternally expressed, noncoding RNAs, which may regulate regional imprinting. Alternative splicing of downstream exons results in different forms of the stimulatory G-protein alpha subunit, a key component of the classical signal-transduction pathway linking receptor-ligand interactions to adenylyl cyclase activation and various cellular responses.

Molecular pathology
GNAS mutations have been linked to pseudohypoparathyroidism types 1a and 1b, Albright hereditary osteodystrophy, pseudopseudohypoparathyroidism, McCune-Albright syndrome, progressive osseus heteroplasia, polyostotic fibrous dysplasia of bone and pituitary tumours.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

pOH

The negative logarithm of the OH- concentration (in moles per liter).
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive
* Ensure that all devices come with the manufacturer's operational manual and that these are reviewed and added to the central file accordingly.
No withdrawals shall be made with respect to the Civil Society/Private Sector Component of the Project until: (a) Government has furnished evidence to the Bank for its approval that the first 20 grants under this component have been made in accordance with the criteria, terms and conditions set forth or referred to in the Operational Manual; and (b) with respect to any Phase II Health District, until the Financial Management Assessment has been completed and the Bank has determined that the relevant Phase U Health District financial management arrangements are acceptable.
The Association updates its operational manual for healthcare facility architects, designers, planners, engineers, contractors, maintenance personnel, and managers.
He conducted a two-month training session for staff, which explained the new business processes and introduced staff to the comprehensive, 1,200-page operational manual. The electronic manual, while perhaps daunting, was organized by work type and comprised highly defined work procedures that emphasized best practices, streamlined processes and made them replicable.
a special policy on indigenous peoples, Operational Manual Statement
The authors, Marshall Kirk and Hunter Madsen, boasted that this was an operational manual for the "overhauling of straight America," by which they meant "converting" America.
(52) However, in 1985, they were incorporated into the Bank's mandatory procedures document, the Operational Manual. (53) The Bank issued guidelines on dam safety in 1977 (54) and 1996, (55) on involuntary resettlement in 1980, (56) 1986, (57) and 1990, (58) on indigenous people in 1982 (59) and 1991, (60) on environmental aspects of dams and reservoirs in 1989, (61) and on environmental assessment in 1989, (62) 1991.
The AxSYM operational manual directs attention to the possibility of bulk solution dispenser misalignment when the dispensers are repositioned incorrectly during the weekly maintenance (4).
The Health Standards and Guidelines for Personal Service operational manual suggest an age requirement of 18 for tattoo clients.
Since 1985, and on the basis of the subsidiarity principle, the EU set up operational mechanisms for the reinforcement of the cooperation of the EU's civil protection services (including mutual assistance principles, operational manual, round the clock operational structure, exchange of experts, etc.).
Crane says the operational manual had to be concise so that it would not be too much for employees to read and absorb.
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