Medical

open-circular DNA

open-circular DNA (OC-DNA)

the non supercoiled conformation adopted by a circular double-stranded DNA MOLECULE, when one or both of the POLYNUCLEOTIDE CHAINS contains a NICK. see SUPERCOILED DNA. Compare COVALENTLY CLOSED CIRCULAR DNA.

Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005

Mentioned in

covalently closed circular DNA
OC-DNA

References in periodicals archive

i) Nicked open-circular DNA that has one strand cut.

Introducing plasmid DNA fingerprinting in the quality control of pDNA vaccine

All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for informational purposes only. This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional.