Ocular melanocytosis

A congenital eye disorder featuring diffuse hyperplasia of melanocytes causing darkening of the iris of the affected eye especially at the pupil margin, brownish discolouration of the episclera, darkening of the fundus, and an increased risk of developing melanomas and GLAUCOMA.

Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

melanocytosis, ocular

A congenital, usually unilateral lesion, characterized by slate grey areas of increased pigmentation. The pigment is curiously not found in the conjunctival epithelium, but is located in the uvea, sclera and episcleral tissues. It may predispose the individual to uveal melanoma. Syn. congenital melanosis oculi. See naevus of Ota.

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References in periodicals archive

Furthermore, our patient had no sign of ocular melanocytosis. Thus, iris mammillations in our case could be easily distinguished from Lisch nodules which are well-defined dome-shaped nodules by slit-lamp examination [1].

Fenicia, "Sturge-Weber Syndrome Associated with Monolateral Ocular Melanocytosis, Iris Mammillations, and Diffuse Choroidal Haemangioma," Case Reports in Ophthalmology, vol.

Bilateral Iris Mammillations in Amblyopic Eyes without Oculodermal Melanocytosis or Neurofibromatosis

In a large clinical series, (5) 8 of 4500 patients presented with bilateral melanoma; no specific syndrome was identified other than ocular melanocytosis for 2 patients.

Ocular melanoma

Congenital ocular melanocytosis predisposes to uveal melanoma, as well as melanoma of the ipsilateral skin, orbit, optic nerve head and brain.

Conjunctival melanocytic lesions: referral refinement part 2: course code: C-16011 O/D

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