neurosarcoma

neurosarcoma

 [noor″o-sahr-ko´mah]

a sarcoma with neuromatous elements.

Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

neu·ro·sar·co·ma

(nū'rō-sar'kō'mă),

A sarcoma with neuromatous elements; includes neurofibrosarcoma, neurogenic sarcoma, and malignant schwannoma.

Farlex Partner Medical Dictionary © Farlex 2012

malignant peripheral nerve sheath tumour

A poorly understood malignancy, presumably of Schwann cell origin, which is thought to arise from the neural crest. It is the most common malignancy of peripheral nerves, and represents 5 to 10% of all soft-tissue tumours. It occurs in the lower extremities in relatively young patients (age 20 to 50). Half of cases occur in patients with neurofibromatosis type 1, in which the male:female ratio is 4:1; 2/3 of MPNSTs arise from neurofibromas, 1/3 arise de novo. Origin from pre-existing schwannomas, ganglioneuromas or phaeochromocytomas are rare; 10% arise in a background of therapeutic radiation.
 
Management
Wide local excision; radiation and chemotherapy have been used with varying degrees of failure.

Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

neurosarcoma

A malignant tumor arising from the cells of Schwann in the sheaths of nerve fibres. Also known as a malignant schwannoma.

Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005