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necrotizing fasciitis

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fasciitis

 [fas″e-i´tis]
inflammation of a fascia.
necrotizing fasciitis a fulminating group A streptococcal infection beginning with severe or extensive cellulitis that spreads to involve the superficial and deep fascia, producing thrombosis of the subcutaneous vessels and gangrene of the underlying tissues. A cutaneous lesion usually serves as a portal of entry for the infection, but sometimes no such lesion is found.
nodular fasciitis (proliferative fasciitis) a benign, reactive proliferation of fibroblasts in the subcutaneous tissues and commonly associated with the deep fascia.
pseudosarcomatous fasciitis a benign soft tissue tumor occurring subcutaneously and sometimes arising from deep muscle and fascia.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

nec·ro·tiz·ing fas·ci·i·tis

a rare soft-tissue infection primarily involving the superficial fascia and resulting in extensive undermining of surrounding tissues; progress is often fulminant and may involve all soft-tissue components, including the skin; usually occurs postoperatively, after minor trauma, or after inadequate care of abscesses or cutaneous ulcers.
See also: group A streptococcal necrotizing fasciitis.
Farlex Partner Medical Dictionary © Farlex 2012

necrotizing fasciitis

n.
Severe, rapidly progressing infection of subcutaneous tissues by streptococci and other bacteria, marked by tissue necrosis and by pain, swelling, and heat in the affected area, usually following an injury or a surgical procedure.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

necrotizing fasciitis

Necrotizing subcutaneous infection Infectious disease A rapidly progressive bacterial infection that spreads along fascial planes which, absent effective therapy–eg, debridement, results in skin breakdown with bleb and bulla formation, small vessel thrombosis and 2º necrosis, leading to subcutaneous anesthesia Agents Streptococci, gram-negative and mixed bacteria
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

necrotizing fasciitis

An uncommon but severe form of tissue damage caused by a streptococcus of Group A. There is widespread inflammation of the layer of fatty tissue under the skin and the effect is so intense that the tissue appears, in places, almost to be ‘eaten away’. The condition features severe pain, marked general upset and intense redness of the overlying skin. Surgical exploration shows grey, swollen fat that can be stripped out easily with the finger. Surgical shock and failure of various organs, such as the kidneys, may occur and the outcome, in inadequately managed or late treated cases is often fatal. Treatment is by massive doses of antibiotics, early radical surgery to remove infected tissue and exposure to high oxygen concentrations in a special chamber (see HYPERBARIC OXYGEN TREATMENT). Inadequate treatment results in a mortality of 30 to 60 per cent.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

Necrotizing fasciitis

A destructive infection which follows severe cellulitis and involves the deep skin and underlying tissues.
Mentioned in: Cellulitis
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.
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References in periodicals archive
WHAT IS NECROTISING FASCIITIS? NECROTISING fasciitis is a rare but serious bacterial infection that affects the tissue beneath the skin and surrounding muscles and organs.
The funding will go towards educational work within the hospital trust and Necrotising Fasciitis recognition and management and to support the professional development of sepsis practice.
Giacalone, "First report of a necrotising fasciitis of the breast following a core needle biopsy," The Breast Journal, vol.
Clinical profile of Necrotising Fasciitis is variable and the clinical course can be erratic.
Menon, "A fulminant case of necrotising fasciitis secondary to rituximab in a patient with rheumatoid arthritis," Annals of the Rheumatic Diseases, vol.
But in cases of necrotising fasciitis, bacteria spread rapidly once they enter the body.
NECROTISING FASCIITIS Is a serious bacterial skin infection that spreads quickly and kills the body's soft tissue.
Necrotising fasciitis with subperiostal Streptococcus canis infection in two puppies.
By the time necrotising fasciitis was diagnosed, it was too late to save her, although doctors amputated her right leg in a desperate attempt to halt the spread of the infection.
But four days later, Sarah - mum to 16-monthold girl Lauren - died on an operating table at Stoke Mandeville Hospital as surgeons tried in vain to stop the rapidly spreading bug, necrotising fasciitis.
However, within a matter of hours, her condition had deteriorated so badly officers at Wrexham police station brought her back to hospital where she later died A post-mortem examination revealed that death was due to septicaemia (blood poisoning) brought on by "venous gangrene" in her leg and necrotising fasciitis - flesh eating bacteria.
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