mitotic activity index
mitotic activity index
A measure of tumour cell proliferation, which is an independent prognostic factor in breast cancer, soft tissue sarcomas and other cancers, and usually determined by the number of mitotic figures per 10 high-power fields. The cutoffs for the number of mitoses/10 HPF for each prognostic group depends on the malignancy.Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
mitotic activity index
Cytometry The number of mitotic figures/10 high power fieldsMcGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
References in periodicals archive
Unfortunately, most available IHC markers are much weaker predictors than the
mitotic activity index. (4) This may be due to the fact that mitotic figures reflect a very small time window in the cell cycle (the M phase), whereas other markers such as MIB1/Ki-67 stain cells in nearly all phases of the cell cycle.
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