Medical

lupus psychosis

lupus psychosis

Neurology A condition seen in 12% to 52% of Pts with SLE, broadly defined to include delusional and severe affective disease Clinical Frank psychosis, atypical psychosis, schizophreniform disorder, and severe affective disorders–eg, major depression and anxiety or panic disorders; some authors argue that major depression, anxiety, or panic may be caused by corticosteroids or may simply represent an appropriate reaction to the illness rather than genuine LP; LP, if it exists, is attributed to an antibody to P protein, a polypeptide in ribosomal phosphoproteins. See Systemic lupus erythematosus.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
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References in periodicals archive
The next case she discussed was forty nine years old women suffering from lupus psychosis.
PSR's 22nd Annual International Rheumatology Conference proceedings-III
Hashimoto, "Accuracy of cerebrospinal fluid IL-6 testing for diagnosis of lupus psychosis. A multicenter retrospective study," Clinical Rheumatology, vol.
Identification of Levels of Serum Amyloid A and Apolipoprotein A1 in Serum Proteomic Analysis of Neuropsychiatric Systemic Lupus Erythematosus Patients
More recently, Matus and coworkers (30) have shown that anti-P antibodies from patients with and without lupus psychosis bind a novel neuronal surface protein that is not present on non-neuronal cells within the central nervous system.
(15) In an open study of 13 patients with lupus psychosis, Mok and colleagues (34) reported a favorable response to a combination of high dose oral corticosteroids and oral cyclophosphamide for 6 months, followed by azathioprine as maintenance immunosuppressive therapy.
Association between lupus psychosis and anti-ribosomal P protein antibodies.
Demystifying neuropsychiatric lupus is it possible?
Lupus psychosis: Differentiation from the steroid-induced state.
Lupus cerebritis: a case study
[52] reporting a strong association between anti-ribosomal P antibodies and lupus psychosis, many other studies tried to confirm the utility of such antibodies in predicting NPSLE.
Kaufman et al., "Association between lupus psychosis and anti-ribosomal P protein antibodies," The New England Journal of Medicine, vol.
Serology of lupus erythematosus: correlation between immunopathological features and clinical aspects
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