ju·ve·nile per·i·o·don·ti·tis

[MIM*170650]

a degenerative periodontal disease of adolescents in which the periodontal destruction is out of proportion to the local irritating factors present on the adjacent teeth; inflammatory changes become superimposed, and bone loss, migration, and extrusion are observed. Two forms are recognized: localized, in which the destruction is limited to the incisors and first molars; and generalized, involving all the teeth.

Synonym(s): periodontosis

Farlex Partner Medical Dictionary © Farlex 2012

aggressive periodontitis type 1

An autosomal dominant condition (OMIM:170650) characterised by severe and protracted gingival infections, leading to tooth loss.

Molecular pathology
Defects in CTSC, which encodes cathepsin C, a ubiquitous lysosomal cysteine proteinase, cause aggressive periodontititis type 1.

juvenile periodontitis

Dentistry Early onset periodontitis of adolescents, ♂:♀ ratio, 3:1, characterized by an early loss of alveolar bone surrounding permanent teeth; 84% have underlying endocrinopathies, 12% systemic disease–eg, DM, neutropenia, Down syndrome, Ehlers-Danlos syndrome, hyperkeratosis palmaris et plantaris, larger histiocytosis X, hypophosphatasia Etiology Actinobacillus actinomycecomitans and others

ju·ve·nile per·i·o·don·ti·tis

(jū'vĕ-nil per'ē-ō-don-tī'tis)

A degenerative periodontal disease of adolescents in which the periodontal destruction is out of proportion to the local irritating factors present on the adjacent teeth; inflammatory changes become superimposed, and bone loss, migration, and extrusion are observed. Two forms are recognized: 1) localized, in which the destruction is limited to the incisors and first molars; and 2) generalized, involving all of the teeth.
Synonym(s): periodontosis.

Medical Dictionary for the Health Professions and Nursing © Farlex 2012

ju·ve·nile per·i·o·don·ti·tis

(jū'vĕ-nil per'ē-ō-don-tī'tis) [MIM*170650]

Degenerative periodontal disease of adolescents in which periodontal destruction is out of proportion to local irritating factors present on adjacent teeth; inflammatory changes become superimposed, and bone loss, migration, and extrusion are observed. Two forms are recognized: localized, in which the destruction is limited to the incisors and first molars; and generalized, involving all teeth.
Synonym(s): localized juvenile periodontitis, periodontosis.

Medical Dictionary for the Dental Professions © Farlex 2012

Mentioned in

References in periodicals archive

Suzuki, "Genetic analysis of juvenile periodontitis in families ascertained through an affected proband," American Journal of Human Genetics, vol.

Diehl, "Reinterpretation of the evidence for X-linked dominant inheritance of juvenile periodontitis," Journal of Periodontology, vol.

BenYehouda, "Multiple therapy approach to juvenile periodontitis: a case report," Quintessence international, vol.

Orthodontic Management in Aggressive Periodontitis

Metronidazole in the treatment of localized juvenile periodontitis. J Clin Periodontol.

Clinical and microbiological effects of adjunctive antibiotics in treatment of localized juvenile periodontitis. A controlled clinical trial.

Diagnostico y alternativas de tratamiento de las enfermedades periodontales agresivas o como manifestacion de enfermedad sistemica en ninos entre 3 y 12 anos de edad. Revision sistematica de la literatura

Early detection of juvenile periodontitis is the key to successful preventive treatment.

A new DNA probe, DMDx test, provides the most accurate early detection of juvenile periodontitis by measuring the specific levels of bacteria in the mouth.

Juvenile periodontitis: no laughing matter

Genco concludes, "Bestatin...has potential for use as an adjunct in the treatment of juvenile periodontitis."

Loe says, "It is most likely that research on juvenile periodontitis may throw additional light and give new clues to understanding the subtleties of the adult, slow-developing, chronic periodontitis."

Mouth immunity; an immune deficiency is associated with a rare periodontal disease