In addition, cancer cells often develop the capacity to utilize increased AR signaling for enhanced
intracrine growth regulation.
Download PDF Brochure@ http://www.marketsandmarkets.com/pdfdownload.asp?id=80206120 Based on signaling type, the market is segmented into paracrine, endocrine, autocrine, juxtacrine, and other signaling types (
intracrine and neuronal signaling).
It is a tightly regulated process, controlled by a number of
intracrine and endocrine feedback loops (Wang et al., 2015; Dusso et al., 2005; Maiti and Beckman, 2007; Perwad et al., 2007).
Endocrine and
intracrine sources of androgens in women: inhibition of breast cancer and other roles of androgens and their precursor dehydroepiandrosterone.
Instead, exogenous FGF2 functioned to reinforce the pluripotency maintenance program of
intracrine FGF2 signaling [74].
In addition, PTHrP has the nuclear localization sequence and also acts via
intracrine action to promote BrCa cell proliferation.
Direct,
intracrine conversion of 25(OH) D to calcitriol by T cells.
Vazquez-Tello et al., "
Intracrine signaling through lipid mediators and their cognate nuclear G-protein-coupled receptors: a paradigm based on PGE2, PAF, and LPA1 receptors," Canadian Journal of Physiology and Pharmacology, vol.
White et al., "The precursor form of IL-1alpha is an
intracrine proinflammatory activator of transcription," Proceedings of the National Academy of Sciences of the United States of America, vol.
Karajannis et al., "Fetal stromal-dependent paracrine and
intracrine vascular endothelial growth factor-a/vascular endothelial growth factor receptor1 signaling promotes proliferation and motility of human primary myeloma cells," Cancer Research, vol.
(10) The human ocular tissues are among the target tissues equipped for
intracrine synthesis and metabolism of oestrogens and androgens.