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infective endocarditis

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in·fec·tious en·do·car·di·tis

, infective endocarditis
endocarditis due to infection by microorganisms.
Farlex Partner Medical Dictionary © Farlex 2012

infective endocarditis

Acute endocarditis; bacterial endocarditis; subacute endocarditis Cardiology An infection of the endocardium which may involve the valves and extend to the myocardium, often occurring in Pts with underlying heart disease Sources of infection Transient bacteremia, common during dental, upper respiratory, urologic, and lower GI diagnostic and surgical procedures; IE may result in vegetations on valves, endocardium and the vascular intima, which may become dislodged and send clots to the brain, lungs, kidneys, or spleen Agents S viridans causes ±50% of IE, staphylococcus and group D streptococcus, Pseudomonas spp, Serratia spp Candida spp Clinical Sx develop slowly over months–subacute or abruptly; fever, fatigue, malaise, headache, night sweats, splinter hemorrhages under fingernails, heart murmurs due to vegetations especially on the mitral valve, splenomegaly, anemia Risk factors Congenital heart disease, ASD, PDA, etc; prior rheumatic heart disease; heart valve defects–eg, mitral insufficiency, prosthetic valves Prophylaxis Antiobiotics before surgery in in at-risk Pts. See Endocarditis.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

in·fec·tious en·do·car·di·tis

, infective endocarditis (in-fek'shŭs en'dō-kahr-dī'tis, in-fek'tiv)
Endocarditis due to infection by microorganisms.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
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References in periodicals archive
Infective endocarditis in adults: Diagnosis, antimicrobial therapy, and management of complications: A scientific statement for healthcare professionals from the American Heart Association.
Demographic and clinical characteristics of patients (N=68) with infective endocarditis due to intravenous nyaope use Age (years), mean (SD) 25.8 (4.5) Male gender, % 97.1 Level of education, mean Grade 10 Employed None Duration of drug use (months), median (IQR) 48 (24-72) NYHA functional class (I/II--III/IV), % 12.6/80.2/7.3 Systolic blood pressure (mmHg), mean (SD) 113.9 (14.8) Diastolic blood pressure (mmHg), mean (SD) 68.7 (11.2) Pulse rate (bpm), mean (SD) 104.3 (22.0) SD = standard deviation; IQR = interquartile range; NYHA = New York Heart Association.
Serban, "Recurrent infective endocarditis of the native aortic valve due to ESBL producing Escherichia coli (E coli) after therapeutic ERCP," Journal of Gastrointestinal and Liver Diseases, vol.
Patients with a low clinical probability of infective endocarditis should not have an echocardiogram performed because it has low positive predictive value and low diagnostic yield, the authors concluded.
Rapid diagnosis, effective treatment and prompt recognition of complications are essential for a good outcome of infective endocarditis, which carries a high morbidity and mortality rate.
Erwin et al., "Global and regional burden of infective endocarditis, 1990-2010: a systematic review of the literature," Global Heart, vol.
Secondary involvement of the anterior mitral leaflet may appear in patients with infective endocarditis affecting the aortic valve because of the intimate anatomic relationship between the two valves.
Although HACEK organisms are documented to comprise up to 3% of all infective endocarditis cases, 60% of individuals with HACEK bacteremia are found to have endocarditis as well.
AMSTERDAM -- Data presented at the annual congress of the European Society of Clinical Microbiology and Infectious Diseases suggest that Propionibacterium acnes may be responsible for many more cases of infective endocarditis than is now believed.
Neurologic complications occur in 20%-40% of patients with infective endocarditis. Mycotic aneurysms are one example of these complications, and although rare, they can confound a patient's recovery and increase morbidity and mortality.
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