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immunotoxin

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immunotoxin

(ĭm′yə-nō-tŏk′sĭn, ĭ-myo͞o′-)
n.
A hybrid molecule formed by binding a toxin to a monoclonal antibody, used to destroy tumor cells.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

immunotoxin

an antibody attached to a specific toxic agent that is used to destroy specific cancer cells. Although experimental at present, these so-called ‘magic bullets’ hold out great hope as a new form of cancer CHEMOTHERAPY.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005
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References in periodicals archive
Alarmingly, maximal immunotoxic levels of [AFB.sub.1] and [AFM.sub.1] in feedstuff's and milk occurred in winter followed by autumn, spring, and summer.
Chronic exposure to low concentration of arsenic is immunotoxic to fish: Role of head kidney macrophages as biomarkers of arsenic toxicity to Ciarias batrachus.
(2007), even small quantities of seeds in the diet of birds were able to cause immunotoxic effects, including depletion of lymphoid cells on the spleen and bursa of Fabricius.
In published literature it is well documented that As is immunotoxic (de la Fuente et al.
Aflatoxin Ochratoxin and Zearalenone have gained immense importance due to carcinogenic hepatotoxic hemotoxic immunotoxic neurotoxic genotoxic and teratogenic biological activities (Mobarak 2007).
Nickel is also identified as haematotoxic immunotoxic neurotoxic genotoxic and pulmonary tox c and carcinogenic agent.
The ubiquitous distribution of both nicotinic and muscarinic cholinergic receptors together with induction of oxidative stress in various tissues [21] may have genotoxic, immunotoxic, nephrotoxic, hepatotoxic, and cardiotoxic effects [22].
Proliferation and cytokine production are two key functions of immune cells and, as such, are important endpoints to examine during any evaluation of immunotoxic potential of a given xenobiotic [18-20].
Silbergeld, "Differential immunotoxic effects of inorganic and organic mercury species in vitro" Toxicology Letters, vol.
Nickel causes skin allergic reaction, aversion in occupationally exposed persons and is haematotoxic, immunotoxic, reproductive poisonous and carcinogenic mediator (Das et al., 2008).
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