Handa, "Cereblon and its downstream substrates as molecular targets of
immunomodulatory drugs," International Journal of Hematology, vol.
When
immunomodulatory drugs were evaluated for TSEP abnormality no significant difference was determined during the 2-year follow-up (Figure 9).
Topical
immunomodulatory drugs and jewelweed are no help
In addition to its ProteoFlow screening capabilities, LigoCyte has
immunomodulatory drug discovery and development activities in support of its own pipeline of therapeutic candidates.
Lenalidomide (Revlimid, Celgene, Switzerland), an analogue of thalidomide, is a kind of the
immunomodulatory drug with potent anti-angiogenic and anti-inflammatory properties.
The Oncologic Drugs Advisory Committee (ODAC) voted 11 to 0 with 1 abstention that carfilzomib's risk-benefit profile is favorable for patients with relapsed and refractory multiple myeloma, who have received at least two prior lines of therapy that included a proteasome inhibitor and an
immunomodulatory drug (IMiD)--the indication under review.
Merrimack Pharmaceuticals, Inc., Cambridge, Mass., has completed enrollment for a Phase IIa pilot study in patients with rheumatoid arthritis with its
immunomodulatory drug candidate, MM-093, a recombinant version of human alpha-fetoprotein (AFP).
In addition to its ProteoFlow(R) screening capabilities, the company has
immunomodulatory drug discovery and development activities in support of its own pipeline of therapeutic candidates.
Lenalidomide is a novel
immunomodulatory drug related to thalidomide, which also has been used effectively in the treatment of multiple myeloma.