Triazoles have been shown to discriminate between fungal and mammalian P450 enzymes better than the
imidazoles do (34).
Sulfonated carbon/silica composite functionalized Lewis acids for one-pot synthesis of 1,2,4,5-tetrasubstituted
imidazoles, 3,4-dihydropyrimidin-2(1H)-ones and for Michael addition of indole to [alpha], [beta]-unsaturated ketones.
In conclusion, we synthesized several
imidazoles and triazoles containing small molecules derived from BH reaction template.
To study the generality of this process, variety of examples were illustrated for the synthesis of 2,4,5-triaryl
imidazoles and results are summarized in Table 3.
Imidazole and its derivatives were purchased from S.D.
Strel'nikov, "Curing of epoxy-anhydride compositions in the presence of
imidazoles," Russian Journal of Applied Chemistry, vol.
Comparative study of topical
imidazoles in dermatophytosis.
The results of the antimicrobial efficacy of the synthesized 2-substituted-4, 5-diphenyl
imidazoles are expressed in Table 1.
The sequential therapy studies all used tinidazole, a relatively new agent in the United States; we don't know whether metronidazole or other
imidazoles are as effective.
With the collaboration of others, he has applied this methodology to the analysis of epoxies cured with
imidazoles, BF3-MEA/epoxy systems, cyanate esters, bismaleimides, and cyanate-epoxies.