Serum biochemical panel showed static to mildly improved albumin (19 g/L; reference interval: 27 to 39 g/L) and stable
hyperglobulinemia (46 g/L; reference interval: 24 to 40 g/L).
Hyperglobulinemia was seen in 22 (44%) patients before treatment and 2 (4%) patients after treatment which was also found to be statistically significant (pless than 0.05).
(1-14) The pathogeneses of SLE and SS are similar, suggesting that aberrations in T and B cells could lead to polyclonal B cell hyperactivity,
hyperglobulinemia, and autoantibody production.
However, 50% of cases involving the plasma cell variant show systemic manifestations, including fever, anemia, and
hyperglobulinemia. (7)
Incipient myelomatosis or 'essential'
hyperglobulinemia with fibrinogenopenia: a new syndrome?
Approximately 50% of patients with the plasma cell variant experience systemic manifestations, including fever, anemia, and
hyperglobulinemia. (2)
The hyperprotidemie and
hyperglobulinemia resulting from the hyper-[gamma] globulin.
The occurrence of either high titer RF,
hyperglobulinemia or a small monoclonal peak support a possible diagnosis of primary Sjogren's syndrome, which should be actively sought by history, ocular examination, and antibody screening.
Serum protein electrophoresis is a useful tool to evaluate hypoglobulinemia and
hyperglobulinemia in reptiles.
Hyperglobulinemia may spuriously elevate measured serum inorganic phosphate levels.
These patients develop transient
hyperglobulinemia and T cell deficiency that improve with specific treatment [11].
The chronic stage includes distinct clinical findings with changes in hematological indices including non-regenerative anemia, thrombocytopenia and leucopenia while biochemical abnormalities may represent hypoalbuminemia,
hyperglobulinemia and hypergamma globulinemia (Bhadesiya and Raval, 2015).