The
horsepox episode "suggests that there are risks that are present today," said Jason Matheny, Iarpa's director.
Zoonotic poxvirus infections include monkeypox, cowpox, buffalopox, feline cowpox,
horsepox, camelpox, and elephantpox.
We compared molecular sequence data from 3 genes and a variable region of the poxvirus genome (Table 1) among BRZ-VACV isolates, available vaccine strains related to those used during the eradication campaign in Brazil, and other VACVs isolated from domestic animals (including endemic buffalopox virus in India [15-17] and
horsepox virus [HSPV] from Asia [18]).
TNX-801 (live
horsepox virus vaccine for percutaneous (scarification) administration) is a novel, live virus vaccine grown in cell culture that is a potential smallpox-preventing vaccine currently in the pre-IND application stage of development.