Medical

histiocytic lesion

histiocytic lesion

An aggregate of histiocytes, which may be benign, indeterminant, or malignant in proliferative potential; to reduce confusion, it has been suggested that histiocytoses be subdivided into different categories
Histiocytic lesions-Behavior classification  
Benign
• Familial histiocytosis with eosinophilia A chronic disease of infants with recurring bacterial infections, diarrhea, eczema, alopecia, associated with immunodeficiency
• Sinus histiocytosis with massive lymphadenopathy Rosai-Dorfman disease A disease most common in adolescent blacks with massive cervical lymphadenopathy as well as enlargement of extranodal (orbit, skin, bone, salivary gland, testis) lymphoid tissues
• Virus-associated hemophagocytic syndrome A condition induced by viral infections, often accompanied by abnormal liver function tests, coagulation assays and pancytopenia Pathology Histiocyte hyperplasia, hemophagocytosis and replacement of native bone marrow elements
Intermediate
• Histiocytosis X, aka Langerhans' cell histiocytosis, see there.
• Reactive hemophagocytic syndrome, see there.
Malignant
• Histiocytic medullary reticulosis see there.
• Histiocytic proliferations, eg—acute monocytic leukemia (FAB M3), histiocytic lymphoma see there, malignant histiocytosis–see there.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
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References in periodicals archive
CD68 may be used to rule out a histiocytic lesion, as abundant xanthomatous change within the schwannoma may introduce that possibility into the differential diagnosis.
Intraparotid Schwannoma
(1) It is a rare, benign, non-Langerhans histiocytic lesion that typically arises in the head and neck, trunk, upper extremities, and lower extremities.
The differential diagnosis of JXG should include other histiocytic lesions, Rosai-Dorfman disease, and infectious causes.
Juvenile xanthogranuloma of the nasal vestibule
Juvenile xanthogranuloma (JXG) is a benign, non-Langerhans cell histiocytic lesion that generally affects infants and children.
Juvenile xanthogranuloma of the tympanic membrane: a case report
Thus, we consider that any histiocytic lesion with admixed prominent eosinophilic infiltrate requires immunohistochemical studies to rule out LCH.
Cutaneous Rosai-Dorfman disease with increased number of eosinophils: coincidence or histologic variant?
Of the tumors, 171 (64%) were primary orbital, 69 (26%) were secondary orbital, and 28 (10%) were metastatic tumors, 27 (10%); inflammatory conditions, 21 (8%); vascular lesions, 20 (7%); mesenchymal tumors, 18 (7%), optic nerve and nerve sheath tumors, 7 (3%); peripheral nerve tumors, 3 (1%), histiocytic lesions, 3 (1%); cystic lesions, 3 (1%), and other lesions, 1 (< 1%).
MORPHOLOGICAL SPECTRUM OF ORBITAL LESIONS AT TERTIARY CARE HOSPITAL IN LAHORE
(7) Soft tissue RDD presentation is with non-specific features, leading to misdiagnosis as benign inflammatory and fibro histiocytic lesions as well as lymphoma and malignant fibrous histiocytoma.
Soft tissue Rosai: Dorfman disease of the sacral region, a very rare disease: case report and review of literature
Histiocytic lesions and proliferations in the lung.
Crystal-storing histiocytosis complicating primary pulmonary marginal zone lymphoma of mucosa-associated lymphoid tissue
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