glycosylation

[gli-ko″-sĭ-la´shun]

the formation of linkages with glycosyl groups.

gly·co·sy·la·tion

(glī'kō-si-lā'shŭn),

Formation of linkages with glycosyl groups, as between d-glucose and the hemoglobin chain to form the fraction hemoglobin A_Ic, the level of which rises in association with the elevated concentration of d-glucose in blood concentration in poorly controlled or uncontrolled diabetes mellitus.
See also: glycosylated hemoglobin.

Farlex Partner Medical Dictionary © Farlex 2012

glycosylation

(glī′kō-sĭ-lā′shən)

The addition of saccharides to proteins or lipids to form a glycoprotein or glycolipid.

gly·co′sy·late′ v.

gly·co·sy·la·tion

(glī'kō-si-lā'shŭn)

Formation of linkages with glycosyl groups, as between d-glucose and the hemoglobin chain to form the fraction hemoglobin A_Ic, the level of which rises in association with the raised blood d-glucose concentration in poorly controlled or uncontrolled diabetes mellitus.
See also: glycosylated hemoglobin

Medical Dictionary for the Health Professions and Nursing © Farlex 2012

glycosylation

the addition of a CARBOHYDRATE to an organic molecule such as a PROTEIN.

Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005

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References in periodicals archive

Hb glycosylation has attained much importance in the modern world due to its use as a scale in the long-term control of diabetes.

Impact of Particle-Size Reduction on the Solubility and Antidiabetic Activity of Extracts of Leaves of Vinca rosea/Partikul Buyuklugunun Azaltilmasinin Vinca rosea Yaprak Ekstresinin Cozunurlugu ve Antidiyabetik Aktivitesi Uzerine Etkisi

218-221###Asn glycosylation###257-260###Asn glycosylation

CLONING AND CHARACTERIZATION OF AUXIN EFFLUX CARRIER GENES ECPIN1C AND ECPIN1D FROM FINGER MILLET ELEUSINECORACANA SUBSP. CORACANA

As discussed previously, Nrf1 is modified by N-linked glycosylation in the ER lumen.

Transcriptional regulation of the 26S proteasome by Nrf1

The TML group has been studying glycosylation mechanisms to elucidate which mutations in patients affect the mechanisms of glycosylation.

The uses of mass spectrometry in translational medicine: Innovative MS hardware and software solutions enable cutting-edge omics research at a distinguished Dutch medical center

To further verify the altered glycopatterns between DN and NDRD patients, lectin blotting was used to characterize the differences of glycosylation in protein level.

Potential Value of Datura stramonium Agglutinin-recognized Glycopatterns in Urinary Protein on Differential Diagnosis of Diabetic Nephropathy and Nondiabetic Renal Disease

High-throughput ESI-MS/MS for glycopeptides, initially separated by LC, allows for the identification and quantification of all detectable features, which, in turn, provides a more detailed account of protein glycosylation patterns.

Comparative Glycopeptide Analysis for Protein Glycosylation by Liquid Chromatography and Tandem Mass Spectrometry: Variation in Glycosylation Patterns of Site-Directed Mutagenized Glycoprotein

EGFR bears twelve N-linked glycosylation sites on the extracellular region (22) and is heavily glycosylated (23).

Cell Surface Sialylated N-Glycan Alterations during Development

Services in Creative BioMart include: Annotate N-linked glycosylation, Annotate O-linked glycosylation, Annotate C-linked glycosylation, Annotate glycationn, Glycan staining or labeling, Glycoprotein purification or enrichment and Glycoproteome and Glycome Analysis by Mass Spectrometry.

Creative BioMart to Expand Its Protein Glycosylation Labeling Service Capacity to Meet Rising Demands

Glycosylation sites analysis was performed using NetNGlyc 1.0 (http://www.cbs.dtu.dk/services/NetNGlyc/) for N-linked glycosylation sites and NetOGlyc 4.0 (http://www.cbs.dtu.dk/services/NetOGlyc/) for O-linked glycosylation sites, respectively.

A Novel Application Potential of GH6 Cellobiohydrolase CtCel6 from Thermophilic Chaetomium thermophilum for Gene Cloning, Heterologous Expression and Biological Characterization

In the following, we will use the term "(NT-) proBNP" (NT-proBNP and/or proBNP) for better reading purposes, since the glycosylation positions are true for both peptides.

Unraveling the Molecular Complexity of O-Glycosylated Endogenous (N-Terminal) pro-B-Type Natriuretic Peptide Forms in Blood Plasma of Patients with Severe Heart Failure