Literature survey on epidemiology and pathology of
gangliocytic paraganglioma. BMC Cancer.
The differential diagnosis of spindle cell tumors includes gastrointestinal stromal tumors (GIST), schwannoma, leiomyoma, neurofibroma,
gangliocytic paraganglioma, and ganglioneuroma [1, 12].
Her final pathology revealed a duodenal
gangliocytic paraganglioma eroding into the pancreas, and all lymph nodes were negative for tumor.
We would like to emphasize that clinicians and pathologist should be aware of the existence of
gangliocytic paraganglioma (GP), which is often misdiagnosed as NET G1 [6].
Corticotropin-producing pulmonary
gangliocytic paraganglioma associated with Cushing's syndrome.
To the Editor.--We wish to comment on the article by Park and Han (1) on
gangliocytic paraganglioma (GP) with lymph node metastasis.
B,
Gangliocytic paraganglioma of the duodenum showing epithelioid neuroendocrine cells (left), schwannian cells (center), and ganglion cell (right) components.
Gangliocytic paraganglioma (GP) is characterized by the triphasic cellular differentiation; epithelioid neuroendocrine cells, spindle cells with Schwann cell-like differentiation, and ganglion cells comprise the tumor.
Gangliocytic paraganglioma of the duodenum composed of spindled, epithelioid, and ganglion cells (arrow in [B] points to ganglion cells) (hematoxylin-eosin, original magnifications X50 [A] and X400 [B]).
Gangliocytic paraganglioma accounts for approximately 9% of all duodenal endocrine tumors.
Gangliocytic paraganglioma has been described to occur in: a.
Gangliocytic paraganglioma (GP) is a rare and distinctive neoplasm of controversial histogenesis and biologic behavior.[1] Although initially thought to arise exclusively in the periampullary region),[1,2] it has recently been described in various sites, including the jejunum, appendix,[3] and stomach.[2]
Gangliocytic paraganglioma is a triphasic tumor) consisting of epithelioid, spindle cell, and ganglion cell-like elements in varying proportions.