[7] reported that
fexofenadine is highly specific [H.sub.1] receptor antagonist with safety profile similar to that of control and does not impair performance in test of driving or psychomotor performance and has been shown to improve the quality of life in patient treated with season allergic rhinitis.
Fexofenadine hydrochloride (FEX) was obtained from Chem Pharma (India).
76 Prasco Labs
Fexofenadine HCI 66993010902 $168,737,541
Fexofenadine (Allegra) is the only antihistamine that doesn't permeate the blood-brain barrier and therefore cannot bind to CNS [histamine.sub.1] ([H.sub.1]) receptors, explained Dr.
* Special Considerations: Cough, upper respiratory tract infection, pyrexia, and otitis media were reported more frequently among 209 pediatric patients taking
fexofenadine twice dally, compared with 229 taking a placebo.
Newer, non-sedating antihistamines like
fexofenadine (Allegra) and Ioratadine (Claritin) don't appear to be as effective.
They took either a Butterbur extract standardized to eight mg of petasine, three times a day, or one tablet of the allergy drug
fexofenadine (Allegra)--a prescription antihistamine.
Newer agents such as loratidine and
fexofenadine are less likely to cause drowsiness.
The nurse received treatment with Allegro (
fexofenadine, 60 mg twice per day; Hoechst, Kansas City, MO, USA), chlorpheniramine (4 mg three time per day; Mine Ta Chemistry Pharmacy Co., Ltd., Tai Chung, Taiwan), and Scanol (acetominophen, 500 mg three times per day; Scanpharm, Birkerod, Denmark) for 14 days.
Research: A prospective, randomized, double-blind, parallel group comparison study of butterbur extract (Ze 339; 8 mg total petasine; one tablet thrice-daily),
fexofenadine (Telfast 180, one tablet once-daily) and placebo was conducted in 330 patients.