e·thy·nyl es·tra·di·ol

a semisynthetic derivative of 17β-estradiol; active by mouth, with a long half-life, it is among the most potent of known estrogenic compounds; used in oral contraceptive preparations.

Synonym(s): ethinyl estradiol

Farlex Partner Medical Dictionary © Farlex 2012

References in periodicals archive

Recently, plant metabolites (phytochemicals) with estrogenic properties have been actively investigated as alternative to synthetic compounds (estradiol and ethynyl estradiol) for therapeutical purpose in humans.

Assessment of estrogenic activity of flavonoids from Mediterranean plants using an in vitro short-term test

2000: Binding to human [alpha]-GST FRs Estradiol-17[beta] (reference chemical) 0.29 I[C.sub.50] 4-Hydroxytamoxifen 1.90 I[C.sub.50] Ethynyl estradiol 2.30 I[C.sub.50] DES 3.20 I[C.sub.50] [alpha]-Zearalanol 6.10 I[C.sub.50] Estrone 6.50 I[C.sub.50] ICI 164, 384 7.00 I[C.sub.50] Estriol 10.00 I[C.sub.50] [beta]-Zearalanol 23.00 I[C.sub.50] Tamoxifen 28.00 I[C.sub.50] Estradiol benzoate -9.00 I[C.sub.50] Zearalenone 31.00 I[C.sub.50] HPTE 250.00 I[C.sub.50] Coumestrol 360.00 I[C.sub.50] Genistein 630.00 I[C.sub.50] 4-t-Octylphenol 2,400.00 I[C.sub.50] Dihydrotesterone 5,900.00 I[C.sub.50] Bisphenol A 36,000.00 I[C.sub.50] Kepone 42,000.00 I[C.sub.50] Matthews et al.

A critical review of methods for comparing estrogenic activity of endogenous and exogenous chemicals in human milk and infant formula. (Research Review)

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