Medical

ectodysplasin A

Also found in: Acronyms.

ectodysplasin A

A protein encoded by EDA on chromosome Xq12-q13.1 that is a type-II membrane protein of the tumour necrosis factor family. It forms a homotrimeric molecule involved in cell-cell signalling during the development of ectodermal tissue.

Molecular pathology
EDA mutations cause anhidrotic ectodermal dysplasia (i.e., X-linked hypohidrotic ectodermal dysplasia).
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