Medical

diffuse axonal injury

Also found in: Dictionary, Acronyms, Wikipedia.

diffuse axonal injury

A form of post-traumatic brain injury which occurs over a broad swath of myelinated tracts of the CNS, resulting in significant neurologic effects ranging from loss of consciousness to persistent vegetative state.

Diagnosis
MRI, if oedematous.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

diffuse axonal injury

Neurology A form of post-traumatic brain damage which results in significant neurologic sequelae in survivors. See Retraction balls.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

dif·fuse ax·o·nal in·jur·y

(di-fyūs' ax'ŏn-ăl in'jŭr-ē)
A common form of brain trauma involving axonal damage (e.g., tearing, sheaving of axon clusters, reactive swelling of surrounding tissue) resulting from acceleration or deceleration movements of the brain matter with accompanying fast rotational forces of the brain and the skull.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
Mentioned in
References in periodicals archive
Recovery of corticospinal tract with diffuse axonal injury: A diffusion tensor image study.
Diffuse Axonal Injury Classification Grade Pathology Duration of Coma I Widespread axonal damage in Brief loss of white matter of cerebral consciousness hemispheres II White matter axonal damage Coma of duration; extending to the corpus recovery process callosum with tissue tear unclear hemorrhages III Pathology of Grade II Immediate coma with diffuse axonal injury posturing and (DAI) with tissue tear incomplete recovery hemorrhages in the brain stem Table 2.
Cause of death Number Percentage Multiple parenchymal hemetomas 9 40 Diffuse axonal injury 5 22 Sub dural bleed 3 14 Vascular injury with diffuse brain edema 2 10 Unrelated to head injury 3 14 DOI: 10.14260/Jemds/2015/1591
As discussed in pathogenesis the key to management of a head injured patient with cerebral edema or diffuse axonal injury is to maintain cerebral perfusion pressure by control of ICP and hemodynamic status.
Mechanisms of injury in blunt or closed traumatic brain injury may be primary, including intracerebral hemorrhage, ischemic infarct, contusion, or diffuse axonal injury; or secondary, producing delayed effects that can include edema, hypoxia, hydrocephalus, increased intracranial pressure, intracranial hemorrhage, or extra or intracranial hematoma.
Primary Brain Injury: Occurs at the time of trauma (Cortical contusions, lacerations, bone fragmentation, diffuse axonal injury and brain stem contusion).
According to Dolinak and Matshes (23), complex skull fractures usually occur as a result of severe head trauma and are associated with extradural and subarachnoid hemorrhages, cerebral edema, and diffuse axonal injury, which are additional markers of severe head injury.
She was in a medically induced coma after suffering a fractured skull and diffuse axonal injury, an injury similar to that suffered by Michael Schumacher in 2013.
Transient lesions in the SCC can be seen in some conditions such as encephalomyelitis, epilepsy, antiepileptic drug toxicity/withdrawal, multiple sclerosis, diffuse axonal injury, and hypoglisemic encephalopathy.
Then aged 15, he suffered a diffuse axonal injury - one of the most devastating types of brain trauma.
Then aged just 15, he suffered a diffuse axonal injury - one of the most devastating types of brain trauma.
by four different mechanisms: 1) diffuse axonal injury duringacceleration/deceleration, 2) tentorium shear strain at the midbrain as a result of the damage caused by the cutting effect from the rigid nature of the tentorium, 3) injury of the neurovascular structures due to edge of tentorium, and 4) hyperextension of the cervical vertebrae injuringthe lower brain stem (9).
Copyright © 2003-2025 Farlex, Inc Disclaimer
All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for informational purposes only. This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional.