diclofenac

[di-klo´fen-ak]

a nonsteroidal anti-inflammatory drug used systemically as the potassium or sodium salt in the treatment of rheumatic and nonrheumatic inflammatory conditions, and as the potassium salt to relieve pain and dysmenorrhea; also applied topically to the conjunctiva as the sodium salt to reduce ocular inflammation or photophobia after certain kinds of surgery and to the skin to treat actinic keratoses.

diclofenac

(dī′klō-fĕn′ăk)

A nonsteroidal anti-inflammatory drug, C₁₄H₁₁Cl₂ NO₂, used in the form of its potassium salt to treat pain.

diclofenac

A non-steroidal anti-inflammatory drug (NSAID) used in the treatment of RHEUMATOID ARTHRITIS and other painful conditions. Brand names are Dicloflex, Diclomax, Motifene, Volraman, Volsaid Retard and Voltarol.

Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

antiinflammatory drug

A drug which inhibits or suppresses most inflammatory responses of an allergic, bacterial, traumatic or anaphylactic origin, as well as being immunosuppressant. They include the corticosteroids (e.g. betamethasone, dexamethasone, fluorometholone, hydrocortisone acetate, loteprednol etabonate, prednisolone, rimexolone, triamcinolone). They are sometimes combined with an antibiotic drug (e.g. betamethasone combined with neomycin or sulfacetamide, dexamethasone combined with neomycin or polymyxin B). Corticosteroids have side effects, such as enhancing the activity of herpes simplex virus, fungal overgrowth, raising intraocular pressure or cataract formation.There are other antiinflammatory drugs that are non-steroidal (NSAID) and have little toxicity. They act mainly by blocking prostaglandin synthesis. These include diclofenac sodium, flurbiprofen sodium, indomethacin, ketorolac, nepafenac and oxyphenbutazone. See immunosuppressants; steroid.

Patient discussion about diclofenac

Q. HELP...has anyone taken Diclofenac? And did you have any side affects? My boyfriend has started this medication and it is messing with his stomach which we know is a side affect BUT we are wondering if it will get better as his body adjust to it or will it always be this way. THANKS FOR ANY HELP! He is taking for inflamation and back pain.

A. Dear brwnis65, I have been on Diclofenac Sodium 75mg EC 2 a day, for about 2 years now. I have a bad back and arthuritis. What works for me is taking it at night AFTER my evening meal. I also take Prilosec in the morning to help with my reflux problem. I have had no problems with the Diclofenac and my stomach. Make sure you drink a full glass of water when you swallow your pill. Good Luck. egglady1955

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References in periodicals archive

Non-steroidal anti-inflammatory drugs (NSAIDs) such as Diclofenac can be used to alleviate the pain, swelling and stiffness caused by rheumatoid arthritis.

China Diclofenac Investigation Market Report, 2019-2023

Bou Vorsak, Cambodia Programme Manager at Birdlife International, said the Ministry of Agriculture, Forestry and Fisheries gave notice of the measures to stop the import, distribution, supply and use of diclofenac in treating any kind of animal that could impact vultures.

Sale and use of diclofenac med banned to save vultures

Presenting a keynote paper on vulture conservation, Prof Dr Rhys Green of Cambridge University said new harmful drugs like Diclofenac have flooded the market and that is why it is urgent to ban these drugs to save vultures.

Call to protect vultures from extinction in South Asia

The company added that Diclofenac 50 mg powder oral solution is now promoted and commercialised in Russia under the brand Dialrapid by CSC Pharmaceuticals.

APR Applied Pharma Research unveils Diclofenac 50 mg powder oral solution for the treatment of migraine and other pain areas in Russia

Results: When a single daily dose of 150mg aspirin is taken with three daily doses of diclofenac sodium (50mg), results show that the anti-platelet effect of aspirin still remains.

EFFECT OF DICLOFENAC SODIUM ON ASPIRIN'S ANTITHROMBOTIC ROLE

Diclofenac sodium is a non-steroidal anti-inflammatory drug (NSAID) commonly used in treating a variety of acute and chronic pain and inflammatory conditions.

Diclofenac Induced Paroxysmal Atrial Fibrillation

Morten Schmidt, M.D., Ph.D., from Aarhus University Hospital in Denmark, and colleagues examined the cardiovascular risks of diclofenac initiation versus initiation of other non-steroidal anti-inflammatory drugs, initiation of acetaminophen, and no initiation using data from a series of 252 nationwide cohort studies.

Increased Cardiovascular Risk for Diclofenac Initiators; Increased risk compared with NSAID non-initiators, initiators of acetaminophen, ibuprofen, naproxen

Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) that's often used to treat arthritis and other painful joint conditions.

Common painkiller tied to increased risk of heart problems

Those beginning diclofenac had a 50% increased 30-day risk for a composite outcome of major adverse cardiovascular events (MACE) compared with individuals who didn't initiate an NSAID or acetaminophen (95% confidence interval for incidence rate ratio, 1.4-1.7).

Diclofenac's cardiovascular risk confirmed in novel Danish study

Dr Morten Schmidt, Aarhus University Hospital, said: "It is time acknowledge the potential health risk of diclofenac and to reduce its use."

Voltarol pills boost heart risk by 50%

With diclofenac, the research team recognized an increased rate of health issues such as irregular heart beat or flutter, stroke, heart failure and heart attack.

Painkiller diclofenac associated with major heart problems

Food and Drug Administration (FDA) has approved a topical diclofenac gel (Voltaren Gel[R]) for arthritic joints amenable to topical treatment, as well as a diclofenac patch (the Flector Patch[R] for acute pain from strains, sprains, and bruises) and a topical diclofenac solution (Pennsaid[R]), indicated for knee OA.

Go Skin Deep for Pain Relief: Topical medications can ease pain and minimize the side effects of oral painkillers