depolarizing block
de·po·lar·iz·ing block
skeletal muscle paralysis associated with loss of polarity of the motor endplate, as occurs following administration of succinylcholine.
Farlex Partner Medical Dictionary © Farlex 2012
de·po·lar·iz·ing block
(dē-pōl'ăr-īz-ing blok) Skeletal muscle paralysis associated with loss of polarity of the motor endplate, as occurs following administration of succinylcholine.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive
The venom of black mambas is highly neurotoxic and contains a combination of a-neurotoxins, which induce postsynaptic blockade of the neuromuscular junctions, and dendrotoxins, which inhibit the voltage-dependent potassium channels, enhancing the release of acetylcholine at the neuromuscular junction, thus producing a neuromuscular block similar to a
depolarizing block [7, 8].
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