Histopathology shows suprabasal clefting, acantholysis, and dyskeratosis with appearance of
corps ronds and grains.
The histopathological finding, irrespective of clinical presentation, characterized by focal changes of acantholysis and presence of dyskeratotic cells resembling Corps ronds and grains associated with suprabasal clefts around the preserved villi, hyperkeratosis and parakeratosis.
Histology showed hyperkeratosis, parakeratosis with some areas showing intraepidermal vesiculation and acantholysis similar to Hailey-Hailey disease, while other areas were more like Darier's disease showing dyskeratotic cells throughout the epidermis, including Corps ronds and grains.
Two types of dyskeratotic cells are present:
corps ronds and grains.
2a & 2b Hyperkeratosis & Corps ronds respectively in Case 1.
HISTOPATHOLOGICAL EXAMINATION: Histopathological examination in both cases shows hyperkeratosis and suprabasal acantholysis, abnormal keratinisation in the form of corps rond in stratum Malpighi and grains in horny layer are also seen.
The histopathological feature noted were hyperkeratosis (100%), suprabasal acantholysis (90%), acantholytic cells (86.6%) and
corps ronds and grains (83.3%).
The histopathological features noted were hyperkeratosis (100%), suprabasal acantholysis (90%), acantholytic cells (86.6%) and
corps ronds and grains (83.3%).