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cinchonism

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cinchonism

 [sin´ko-nizm]
toxicity due to overdosage of cinchona alkaloids; symptoms are tinnitus and slight deafness, photophobia and other visual disturbances, mental dullness, depression, confusion, headache, and nausea. Called also quininism.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

cin·cho·nism

(sin'kō-nizm),
Poisoning by cinchona, quinine, or quinidine; characterized by tinnitus, headache, deafness, and occasionally, anaphylactoid shock.
Synonym(s): quininism
Farlex Partner Medical Dictionary © Farlex 2012

cinchonism

(sĭng′kə-nĭz′əm, sĭn′chə-)
n.
A pathological condition resulting from an overdose of cinchona bark or its alkaloid derivatives and marked by headache, dizziness, hearing loss, and ringing in the ears.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
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Toxic levels of quinine sulfate may give rise to cinchonism, a condition characterized by tinnitus, visual disturbances, vertigo, nausea, vomiting, abdominal pain, and deafness, even in patients taking 200 to 300 mg qd; other severe side effects include cardiac arrhythmias, thrombocytopenias, and hypersensitivity reactions.
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